臨床研究センターについて

沿革

４８年、我が国の難病対策の一環として、既存のアレルギーセンター（昭和２９年指定ー昭和３２年設立）を母体にして、病態・発症において共に免疫学的機序と深く関わる慢性関節リウマチと関連疾患を加えて、リウマチ・アレルギー疾患の基幹施設に指定され、昭和５１年より国立病院における初めての臨床研究部として発足しました。当臨床研究部の特色としては、機能付与されたリウマチ・アレルギー疾患という複数診療科の関わる疾患の特殊性を生かすべく、臨床研究部を軸に複数科が常に協力して日常診療、臨床研究に当たってきたことです。アレルギー部門では、アレルギー疾患をアレルゲンに対するホストの種々の反応の面、及び攻撃因子であるアレルゲンの側からその分析を行うというように、アレルギー反応を多角的に研究することを特徴としています。また、リウマチ部門では、基礎、内科、整形外科が一体となって、関節リウマチの発症病態機序、診断方法、薬物治療、人工関節の開発等、の研究を進めてきました。すなわち疫学・臨床統計からはじまり、病態・発症機序の解明、抗原分析、そして新規診断方法、新規治療法の開発まで一施設でリウマチ・アレルギー疾患を包括的に研究・診療できる体制にあることが特徴です。

平成１１年３月の国立病院・療養所の再編成計画の見直しにおいて、当院が政策医療"免疫異常"の高度専門医療施設（準ナショナルセンター）に指定されたのに伴い、これまでの１部５室の臨床研究部は、平成１２年１０月からは、国立病院・療養所における初めての臨床研究センターとして５部１５室に拡大改組されました。平成16年4月からの独立行政法人化後においてもこれまでの研究の伝統を引き継ぎつつ、国立病院機構相模原病院全体の臨床研究の向上に向けて、パーキンソン病をはじめとする神経疾患や自己免疫性肝炎や各種消化器がんについての基礎、臨床研究も少しずつ加わりつつあります。

組織図

アレルゲン研究室（Division of Allergen Research）

薬剤過敏症研究室（Division of Drug Hypersensitivity）

疫学統計研究室 (Division of Epidemiological Statistics)

治験管理室(Division of Clinical Trial Management)

気管支喘息研究室(Division of Asthma)

皮膚アレルギー研究室　(Division of Skin Allergy)

食物アレルギー研究室 (Division of Food allergy)

鼻アレルギー研究室 (Division of Nasal Allergy)

内科系リウマチ研究室(Division of Rheumatic Diseases)

外科系リウマチ研究室 (Division of Rheumatic Diseases, Surgery Division)

神経難病研究室 (Division of Intractable Neurological Diseases)

腫瘍免疫研究室 (Division of Tumor Immunology)

臨床外科免疫研究室 (Division of Surgical Immunology)

分子生物学研究室 (Division of Molecular Biology)

臨床免疫学研究室 (Division of Clinical Immunology)

業績

成人アレルギー

2023年度

【欧文原著・総説・著書】

タイトル：Development of a new HISCL automated CXCL9 immunoassay
筆　　者：Hasegawa T, Yoshida M, Watanabe S, Kondo T, Asada H, Nakagawa A, Tomii K, Kameda M, Otsuka M, Kuronuma K, Chiba H, Katayanagi S, Miyazaki Y, Mori A.
誌 名 等：Scientific Reports .2023 Apr 1;13(1):5342.

タイトル：Longitudinal changes in the prevalence of adult asthma: An epidemiological survey among Japanese salaried employees and their dependents using healthcare insurance claim from 1999 to 2019
筆　　者：Nagayama K, Fukutomi Y, Nakatani E, Hamada Y, Irie M, Azekawa K, Tomita Y, Watai K, Kamide Y, Sekiya K, Nakamura Y, Okada C, Shimoda T, Nagao M, Fujisawa T, Taniguchi M.
誌 名 等：Allergology International. 2023 Apr;72(2):245-251.

タイトル：Prevalence of Allergic Diseases across All Ages in Japan: A Nationwide Cross-Sectional Study Employing Designated Allergic Disease Medical Hospital Network
筆　　者：Ito Y, Kato T, Yoshida K, Takahashi K, Fukutomi Y, Nagao M, Fukuie T, Matsuzaki H, Gotoh M, Tanaka A, Konno S, Tezuka J, Nakamura Y, Adachi Y
誌 名 等：Japan Medical Association Journal.2023 Apr 14;6(2):165-174

タイトル：Frailty and muscle weakness in elderly patients with asthma and their association with cumulative lifetime oral corticosteroid exposure
筆　　者：Ryu K, Fukutomi Y, Nakatani E, Iwata M, Nagayama K, Yano K, Nakamura Y, Hamada Y, Watai K, Kamide Y, Sekiya K, Araya J, Kuwano K, Taniguchi M.
誌 名 等：Allergology International. 2023 Apr;72(2):252-261.

タイトル：Characterization and cluster analyses of elderly asthma in comparison with non-elderly asthma patients in Japan
筆　　者：Suzukawa M, Ohta K, Hashimoto H, Oyamada Y, Miki M, Ogawara M, Inoue Y, Saito AM, Fukutomi Y, Kobayashi N, Taniguchi M; NHOM-Asthma study group.
誌 名 等：Annals of Allergy, Asthma and Immunology. 2023 May;130(5):607-616.e3.

タイトル：Omalizumab ameliorates extra-respiratory symptoms in patients with aspirin-exacerbated respiratory disease
筆　　者：Hayashi H, Fukutomi Y, Mitsui C, Kajiwara K, Watai K, Tomita Y, Kamide Y, Tsuburai T, Sekiya K, Ishii M, Hasegawa Y, Taniguchi M
誌 名 等：Journal of Allergy and Clinical Immunology.2023 Jun;151(6):1667-1672.e2. Epub 2023 Mar 24.

タイトル：Phenotype characterization and biomarker evaluation in moderate to severe type 2-high asthma
筆　　者：Imoto S, Suzukawa M, Fukutomi Y, Kobayashi N, Taniguchi M, Nagase T, Ohta K
誌 名 等：Asian Pacific Journal of Allergy and Immunology. 2023 Jun 11

タイトル：Computed tomography findings of paranasal sinuses in patients with eosinophilic granulomatosis with polyangiitis: Comparison with other eosinophilic sinus diseases and clinical relevance of their severity
筆　　者：Iwata M,Fukutomi Y,Hamada Y,Nakamura Y,Watai K, Kamide Y,Ishii T,Taniguchi M,Sekiya K
誌 名 等：Allergology International.2023 Jul;72(3):428-436.

タイトル：A European-Japanese study on peach allergy: IgE to Pru p 7 associates with severity
筆　　者：Kallen EJJ, Revers A, Fernández-Rivas M, Asero R, Ballmer-Weber B, Barreales L, Belohlavkova S, de Blay F, Clausen M, Dubakiene R, Ebisawa M, Fernández-Perez C, Fritsche P, Fukutomi Y, Gislason D, Hoffmann-Sommergruber K, Jedrzejczak-Czechowicz M, Knulst AC, Kowalski ML, Kralimarkova T, Lidholm J, Metzler C, Mills ENC, Papadopoulos NG, Popov TA, Purohit A, Reig I, Seneviratne SL, Sinaniotis A, Takei M, Versteeg SA, Vassilopoulou AE, Vieths S, Welsing PMJ, Zwinderman AH, Le TM, Van Ree R
誌 名 等：Allergy. 2023 Sep;78(9):2497-2509.

タイトル：Analysis of the Factors That Affect the Detection Duration of SARS-CoV-2 in Loop Mediated Isothermal Amplification among COVID-19 Inpatients
筆　　者：Maruyama K，Sekiya K，Yanagida N，Nakayama K，Kushida Y，Yasuda S，Fukumoto D，Hosoya S，Moriya H，Katsumi M
誌 名 等：Japanese Journal of Infectious Diseases . 2023 Sep 22;76(5):282-288.

タイトル：Leukotriene antagonists reduce epileptic seizures-related hospitalization in older adult populations with allergic rhinitis or asthma: A population-based cohort study using the Shizuoka Kokuho database: The Shizuoka Study
筆　　者：Imaichi Y, Nakatani E, Fukutomi Y, Kuriyama N, Mori K, Sugawara A
誌 名 等：Epilepsia Open. 2023 Oct 25.

タイトル：Validation of asthma discrimination criteria using health insurance claims data in Japan: Additional proposals for more specific criteria. .
筆　　者：Hamada Y, Nakatani E, Nagahama T, Nagai K, Nagayama K, Tomita Y, Kamide Y, Sekiya K, Taniguchi M, Fukutomi Y
誌 名 等：Allergol Int. 2023 Oct;72(4):594-596.

タイトル：Serum MMP3 and IL1-RA levels may be useful biomarkers for detecting asthma and chronic obstructive pulmonary disease overlap in patients with asthma
筆　　者：Takada K, Suzukawa M, Tashimo H, Ohshima N, Fukutomi Y, Kobayashi N, Taniguchi M, Ishii M, Akishita M, Ohta K.
誌 名 等：World Allergy Organization Journal. 2023 Nov 9;16(11):100840.

タイトル：Allergic bronchopulmonary aspergillosis with atopic, nonatopic, and sans asthma-Factor analysis
筆　　者：Okada N, Yamamoto Y, Oguma T, Tanaka J, Tomomatsu K, Shiraishi Y, Matsuse H, Shimoda T, Kimura H, Watai K, Harada T, Fujita Y, Obase Y, Suzukawa M, Suzuki J, Takayanagi N, Ishiguro T, Masaki K, Fukunaga K, Asano K.
誌 名 等：Allergy.2023 NOV.;78(11): 2933-2943.

タイトル：Hypersensitivity to intravenous succinate corticosteroids in patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory disease
筆　　者：Taniguchi M，Sato A，Mita H
誌 名 等：Frontiers in Allergy. 2023 Nov 10:4:1145809.

タイトル：Clinical characteristics of allergic bronchopulmonary mycosis caused by Schizophyllum commune
筆　　者：Oguma T, Ishiguro T, Kamei K, Tanaka J, Suzuki J, Hebisawa A, Obase Y, Mukae H, Tanosaki T, Furusho S, Kurokawa K, Watai K, Matsuse H, Harada N, Nakamura A, Shibayama T, Baba R, Fukunaga K, Matsumoto H, Ohba H, Sakamoto S, Suzuki S, Tanaka S, Yamada T, Yamasaki A, Fukutomi Y, Shiraishi Y, Toyotome T, Fukunaga K, Shimoda T, Konno S, Taniguchi M, Tomomatsu K, Okada N, Asano K; Japan ABPM Research Program.
誌 名 等：Clinical and Translational Allergy.2024 JAN .;14:e12327

タイトル：Anisakis allergy versus gastric anisakiasis: A case of repeated Anisakis-associated symptoms
筆　　者：Hamada Y, Sugano S, Kamide Y, Sekiya K, Fukutomi Y.
誌 名 等：Journal of Allergy and Clinical Immunology: Global.2024 JAN.;3:100207

タイトル：Treatable Traits in Asthma: The importance of extra- pulmonary traits - GERD, CRSwNP, Atopic Dermatitis, and Depression/Anxiety
筆　　者：McDonald VM, Hamada Y, Agusti A, Gibson PG
誌 名 等：Journal of Allergy and Clinical Immunology: In Practice. 2024 JAN； Epub 2024 Jan 24.

タイトル：A randomized double-blind placebo-controlled trial of an inhibitor of plasminogen activator inhibitor-1 (TM5614) in mild to moderate COVID-19
筆　　者：Hirai T, Asano K, Ito I, Miyazaki Y, Sugiura H, Agirbasli M, Kobayashi S, Kobayashi M, Shimada D, Natsume I, Kawasaki T, Ohba T, Tajiri S, Sakamaki F, Mineshita M, Takihara T, Sekiya K, Tomii K, Tomioka H, Kita H, Nishizaka Y, Fukui M, Miyata T, Harigae H.
誌 名 等：Scientific Reports. 2024 Jan 2;14(1):165.

タイトル：Reduction in ANCA levels associated with mepolizumab add-on treatment in eosinophilic granulomatosis with polyangiitis: Case series and literature review.
筆　　者：Kamide Y, Watai K, Nakamura Y, Iwata M, Fukutomi Y, Taniguchi M, Sekiya K.
誌 名 等：Allergol Int. 2024 Jan;73(1):180-183.

タイトル：Increased allergic episodes induced by Japanese apricot following the Cupressaceae pollen season in adult patients mono-sensitized to Pru p 7.
筆　　者：Hamada Y, Maruyama N, Saito A, Iwata M, Nakamura Y, Kamide Y, Sekiya K, Lidholm J, Fukutomi Y.
誌 名 等：Allergol Int. 2024 Jan;73(1):168-170

タイトル：Effects of raw seafood on the risk of hypersensitivity reaction recurrence in patients with an Anisakis allergy: A retrospective observational study in Japan.
筆　　者：Hamada Y, Nakatani E, Watai K, Iwata M, Nakamura Y, Ryu K, Kamide Y, Sekiya K, Fukutomi Y.
誌 名 等：Allergol Int. 2024 Jan;73(1):171-173.

タイトル：Uncovering severe patient group with pollen-related extrarespiratory allergic symptoms: A year-long diary survey in Japan
筆　　者：Fukutomi Y, Tanaka H, Sekiya K, Watai K, Hamada Y, Iwata M, Saito A, Okabe K, Sugiyama A, Fukushima T, Oshikawa C, Uetake H, Yoshisue H, Irie T, Kishikawa R.
誌 名 等：The Journal of Allergy and Clinical Immunology: In Practice. 2024 Feb 19:S2213-2198(24)00167-3.

タイトル：Metagenomic gut microbiome analysis of Japanese patients with multiple chemical sensitivity/idiopathic environmental intolerance
筆　　者：Watai K, Suda W, Kurokawa R, Sekiya K, Hayashi H, Iwata M, Nagayama K, Nakamura Y, Hamada Y, Kamide Y, Fukutomi Y, Nakabayashi T, Tanaka K, Kamita M, Taniguchi M, Hattori M.
誌 名 等：BMC Microbiology. 2024 Mar 11;24(1):84.

【和文原著】

タイトル：地域医療支援病院における抗菌薬適正使用支援チームへの薬剤師専従化による抗菌薬適正使用の影響調査
筆　　者：丸山 浩平, 森谷 宏光, 細谷 智, 関谷 潔史, 福元 大介, 安田 秀平, 佐藤 美咲, 鈴村 史帆, 勝海 学
誌 名 等：日本化学療法学会雑誌 2023．5；71（3）：311-325

タイトル：セフトリアキソン投与終了2ヵ月後に発症した偽胆石による総胆管結石症の1例
筆　　者：丸山 浩平,瀧川 政和,大高 史聖,足立 遼子,佐藤 美咲,吉川 直美,川邊 元子,森 達也,関谷 潔史
誌 名 等：日本病院薬剤師会雑誌 2023．11；59（11）：1249-1253

タイトル：市中発症の非重症胆道感染症に対する推奨抗菌薬設定の効果
筆　　者：丸山 浩平,足立 遼子, 関谷 潔史
誌 名 等：日本環境感染学会誌　2023．10；39（1）：20-28

2022年度

【欧文原著・総説・著書】

タイトル：Th17-Dependent Nasal Hyperresponsiveness Is Mitigated by Steroid Treatment.
筆　　者：Ueda S, Miura K, Kawasaki H, Ogata S, Yamasaki N, Miura S, Mori A, and Kaminuma O
誌 名 等：Biomolecules 2022 May,;12(5):674

タイトル：Classifications of moderate to severe asthma phenotypes in Japan and analysis of serum biomarkers: A Nationwide Cohort Study in Japan (NHOM Asthma Study)population
筆　　者：Suzukawa M, Ohta K, Fukutomi Y, Hashimoto H, Endo T, Abe M, Kamide Y, Yoshida M, Kikuchi Y, Kita T, Chibana K, Tanimoto Y, Hyodo K, Takata S, Inui T, Yasui M, Harada Y, Sato T, Sakakibara Y, Minakata Y, Inoue Y, Tamaki S, Shinohara T, Takami K, Tsubakihara M, Oki M, Wakamatsu K, Horiba M, Ideura G, Hidaka K, Saito AM, Kobayashi N, Taniguchi M
誌 名 等：Allergology International.2023 Jan;72(1):63-74.

タイトル：Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma
筆　　者：Itakura K, Fujino N, Kamide Y, Saito I, Yamada M, Okutomo K, Tsukita Y, Saito T, Ichikawa T, Numakura T, Kyogoku Y, Aizawa H, Ono Y, Matsumoto S, Hussell T, Taniguchi M, Ichinose M, Sugiura H.
誌 名 等：Allergology International.2022 Jul.;71(3)383-394

タイトル：Identification of asthma cases in Japan using health insurance claims data: Positive and negative predictive values of proposed discrimination criteria: A single-center study
筆　　者：Hamada Y, Nakatani E, Nagahama T, Nagai K, Nagayama K, Tomita Y, Sekiya K, Taniguchi M, Fukutomi Y.
誌 名 等：Allergology International. 2023 Jan.;72(1):75-81.

タイトル：Identification of fungi causing humidifier lung: 2 rare cases and a review of the literature
筆　　者：Ryu K, Fukutomi Y, Sekiya K, Saito A, Hamada Y, Watai K, Kamide Y, Taniguchi M, Araya J, Kuwano K, Kamei K.
誌 名 等：Asia Pacific Allergy.2022 Oct.;12(4):e43

タイトル：Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness
筆　　者：Uda N, Ogata S, Yamasaki N, Miura S, Hosomi N, Mori A, Gotoh M, Miura K, Kaminuma O
誌 名 等：Journal of Pharmacological Sciences.2022 Oct.; 150(4): 275-278

タイトル：The role of omalizumab in NSAID-exacerbated respiratory disease: a narrative review
筆　　者：Taniguchi M, Heffler E, Olze H, White A, Côrte-Real J, Olsson P, Lazarewicz S
誌 名 等：The Journal of Allergy and Clinical Immunology. In Practice.2022 Oct;10(10):2570-2578

タイトル：Treatments of refractory eosinophilic lung diseases with biologics
筆　　者：Asano K, Suzuki Y, Tanaka J, Kobayashi K, Kamide Y
誌 名 等：Allergology International.2022 Nov.; S1323-8930(22): 00121-6

タイトル：Editorial: Pathophysiological and clinical advances in asthmatic inflammation from the nasopharynx to the peripheral airway in the respiratory tract systems
筆　　者：Koga Y, Kamide Y, Hisada T, Ishizuka T.
誌 名 等：Frontiers in Pharmacology.2023 Jan.;14:1037610

タイトル：Barrier Factors of Adherence to Dupilumab Self-Injection for Severe Allergic Disease: A Non-Interventional Open-Label Study
筆　　者：Hosoya K, Komachi T, Masaki K, Suzaki I, Saeki H, Kanda N, Nozaki M, Kamide Y, Matsuwaki Y, Kobayashi Y, Ogino E, Osada SI, Usukura N, Kurumagawa T, Ninomia J, Asako M, Nakamoto K, Yokoi H, Ohyama M, Tanese K, Kanzaki S, Fukunaga K, Ebisawa M, Okubo K.
誌 名 等：Patient Preference and Adherence. 2023 Mar 27;17:861-872.

【和文原著】

タイトル：BNT162ｂ2ｍＲＮＡ COVID-19ワクチン接種後の抗体価に関する要因の解析
筆　　者：丸山 浩平,足立 遼子,関谷 潔史
誌 名 等：日本環境感染学会誌 2022．11；37（6）：248-255

2021年度

【欧文原著・総説・著書】

タイトル：New Clinical Diagnostic Criteria for Allergic Bronchopulmonary Aspergillosis/Mycosis and its Validation
筆　　者：Asano K, Hebisawa A, Ishiguro T, Takayanagi N, Nakamura Y, Suzuki J, Okada N, Tanaka J, Fukutomi Y, Ueki S, Fukunaga K, Konno S, Matsuse H, Kamei K, Taniguchi M, Shimoda T, Oguma T; Japan ABPM research program.
誌 名 等：Journal of Allergy and Clinical Immunology.2021 Apr.;147(4):1261-1268

タイトル：Occupational Hypersensitivity Pneumonitis in a Japanese Citrus Farmer
筆　　者：Kutsuzawa N, Takihara T, Shiraishi Y, Kajiwara H, Imanishi T, Fukutomi Y, Kamei K, Takahashi M, Enokida K, Horio Y, Ito Y, Hayama N, Oguma T, Asano K.
誌 名 等：Internal Medicine.May.; 2021 Nov.;60(22):3581-3584. Epub 2021 May 22.

タイトル：Respiratory sensitization to insect allergens: Species, components and clinical symptoms
筆　　者：Fukutomi Y, Kawakami Y.
誌 名 等：Allergology International.2021 Jul.;70(3):303-312

タイトル：Genome-wide association study reveals an association between the HLA-DPB1 ∗ 02:01:02 allele and wheat-dependent exercise-induced anaphylaxis
筆　　者：Fukunaga K, Chinuki Y, Hamada Y, Fukutomi Y, Sugiyama A, Kishikawa R, Fukunaga A, Oda Y, Ugajin T, Yokozeki H, Harada N, Suehiro M, Hide M, Nakagawa Y, Noguchi E, Nakamura M, Matsunaga K, Yagami A, Morita E, Mushiroda T.
誌 名 等：Am J Hum Genet. 2021 Aug.;108(8):1540-1548. Epub 2021 Jul 10.

タイトル：Suppressive effect of dexamethasone on murine Th9 cell-mediated nasal eosinophilic inflammation.
筆　　者：Koyama T, Miura K, Yamasaki N, Ogata S, Ito D, Saeki M, Hiroi T, Mori A, Kaminuma O
誌 名 等：Asia Pacific Allergy.2021 Jul.;11(3):e25

タイトル：L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation.
筆　　者：Ito D, Miura K, Saeki M, Yamasaki N, Ogata S, Koyama T, Hiroi T, Mori A, Endou H, Hayashi K, Kaminuma O
誌 名 等：Asia Pacific Allergy.2021 Jul.;11(3):e23

タイトル：Eosinophil ETosis-mediated release of galectin-10 in eosinophilic granulomatosis with polyangiitis
筆　　者：Fukuchi M,Kamide Y,Ueki S,Miyabe Y,Konno Y,Oka N,Takeuchi H,Koyota S,Hirokawa M,Yamada T,C N Melo R,F Weller P,Taniguchi M
誌 名 等：Arthritis & Rheumatology. 2021 Sep;73(9):1683-1693

タイトル：Prevalence of inhaled allergen-specific IgE antibody positivity in the healthy Japanese population
筆　　者：Tanaka J, Fukutomi Y, Shiraishi Y, Kitahara A, Oguma T, Hamada Y, Watai K, Nagai T, Taniguchi M, Asano K.
誌 名 等：Allergology International. 2022 Jan.;71(1):117-124. Epub 2021 Sep 1.

タイトル：Association between the severity of chronic spontaneous urticaria and sleep-disordered breathing
筆　　者：Nagayama K, Watai K, Sekiya K, Iwata M, Hashimoto Y, Nakamura Y, Miyake A, Ryu K, Hayashi H, Ohmatsu H, Kamide Y, Fukutomi Y, Taniguchi M
誌 名 等：Allergology International. 2022 Jan.;71(1):103-108. Epub 2021 Sep 10.

タイトル：Low-dose mepolizumab is effective as an add-on therapy for treating long-lasting peripheral neuropathy in patients with eosinophilic granulomatosis with polyangiitis
筆　　者：Nakamura Y, Fukutomi Y, Sekiya K, Kajiwara K, Kawasaki Y, Fujita N, Nagayama K, Iwata M, Iwamoto K, Yano K, Hamada Y, Watai K, Ryu K, Hayashi H, Kamide Y, Taniguchi M.
誌 名 等：Modern Rheumatology. 2022 Feb.;32(2):387-395.

タイトル：Structure-based prediction of the IgE epitopes of the major dog allergen Can f 1.
筆　　者：Nakatsuji M, Sugiura K, Suda K, Sakurai M, Ubatani M, Muroya H, Okubo R, Noguchi R, Kamata Y, Fukutomi Y, Ishibashi O, Nishimura S, Inui T.
誌 名 等：The FEBS Jounal. 2022 Mar.;289(6):1668-1679. Epub 2021 Nov 7.

タイトル：Increased Prevalence of Atopic Dermatitis in Children Aged 0-3 Years Highly Exposed to Parabens
筆　　者：Arafune J, Tsujiguchi H, Hara A, Shimizu Y, Hori D, Nguyen TTT, Suzuki F, Hamagishi T, Yamada Y, Nakamura H, Yoshikawa T, Hayashi K, Shibata A, Fukutomi Y, Ohya Y, Yamamoto-Hanada K, Muto G, Hirota R, Konoshita T, Kambayashi Y, Nakamura H.
誌 名 等：International Journal of Environmental Research and Public Health.2021 Nov.;18(21):11657

タイトル：The First Death in Japan Attributed to COVID-19:A Brief Report
筆　　者：Nagayama K，Watai K，Sekiya K，Kamide Y，Kaneda G
誌 名 等：Cureus. 2021 Dec.;13(12):e20721

タイトル：Miliary pattern on chest imaging caused by adenocarcinoma
筆　　者：Hamada Y, Iwata M, Sekiya K
誌 名 等：CMAJ.2022 Feb.;194(7):E259-E260

タイトル：Allergic fungal diseases in theupper and lower airways
筆　　者：Shigeharu U, Fukutomi Y, Miyabe Y，Yamada T,Oguma T，and Asano K
誌 名 等：Eosinophilic Lung Diseases (ERS Monograph).2022 Mar.;:119–140

タイトル：Perspectives on the Efficacy of Benralizumab for Treatment of Eosinophilic Granulomatosis With Polyangiitis
筆　　者：Koga Y, Aoki-Saito H, Kamide Y, Sato M, Tsurumaki H, Yatomi M, Ishizuka T, Hisada T.
誌 名 等：Frontiers in Pharmacology.2022 Mar.;13:865318

小児アレルギー

2023年度

【欧文原著・総説・著書】

タイトル：Differential patterns of fish sensitization in Asian populations: Implication for precision diagnosis
筆　　者：Wai CYY, Leung NYH, Leung ASY, Fusayasu N, Sato S, Xu KJY, Yau YS, Rosa Duque JS, Kwan MYW, Cheng JWCH, Chan WH, Chua GT, Lee QU, Luk DCK, Ho PK, Wong JSC, Lam ICS, Wong GWK, Ebisawa M, Leung TF
誌 名 等：Allergology International . 2023 Jul;72(3):458-465. Epub 2023 Apr 7.

タイトル：Analysis of drug-induced anaphylaxis cases using the Japanese Adverse Drug Event Report (JADER) database - secondary publication
筆　　者：Sugizaki C, Sato S, Yanagida N, Ebisawa M
誌 名 等：Allergology International . 2023 Oct;72(4):580-587. Epub 2023 Apr 12.

タイトル：Randomized controlled trial of slow peanut oral immunotherapy in young children: SmaChO study protocol
筆　　者：Uhl C, Sverremark-Ekström E, Borres M, Ebisawa M, Melén E, Mäkelä MJ, Konradsen JR, Vickery BP, Asarnoj A, Nilsson C
誌 名 等：Clinical & Experimental Allergy . 2023 May;53(5):594-597. Epub 2023 Apr 26.

タイトル：Refractory Anaphylaxis: A New Entity for Severe Anaphylaxis
筆　　者：Pouessel G, Deschildre A, Dribin TE, Ansotegui IJ, Cardona V, Chinthrajah RS, Ebisawa M, Muraro A, Roberts G, Sampson HA, Waserman S, Wood RA, Worm M, Turner PJ
誌 名 等：The Journal of Allergy and Clinical Immunology: In Practice . 2023 Jul;11(7):2043-2048. Epub 2023 May 10.

タイトル：Specific IgE to individual allergen components: Milk and egg
筆　　者：Sato S, Ebisawa M
誌 名 等：Elsevier Reference Collection in Food Science.2023 Jun 1

タイトル：Relationship between eliciting doses and the severity of allergic reactions to food
筆　　者：Yanagida N, Sato S, Ebisawa M
誌 名 等：Current Opinion in Allergy and Clinical Immunology . 2023 Jun 1;23(3):226-232. Epub 2023 Mar 28.

タイトル：Food allergy: new therapeutic options open deeper questions
筆　　者：Fiocchi A, Ebisawa M
誌 名 等：Current Opinion in Allergy and Clinical Immunology . 2023 Jun 1;23(3):216-217.

タイトル：Optimization of the allergen classification of the International Classification Of Diseases, 11th Revision (ICD-11)
筆　　者：Tanno LK, Briand Y, Mary M, Khan DA, Sublett JL, Corbett ML, Pawankar R, Del Giacco S, Torres MJ, Ansontegui IJ, Ebisawa M, Martin B, Demoly P
誌 名 等：Journal of Allergy and Clinical Immunology . 2023 Jun;151(6):1655-1659.e3. Epub 2023 Apr 4.

タイトル：A European-Japanese study on peach allergy: IgE to Pru p 7 associates with severity
筆　　者：Kallen EJJ, Revers A, Fernández-Rivas M, Asero R, Ballmer-Weber B, Barreales L, Belohlavkova S, de Blay F, Clausen M, Dubakiene R, Ebisawa M, Fernández-Perez C, Fritsche P, Fukutomi Y, Gislason D, Hoffmann-Sommergruber K, Jedrzejczak-Czechowicz M, Knulst AC, Kowalski ML, Kralimarkova T, Lidholm J, Metzler C, Mills ENC, Papadopoulos NG, Popov TA, Purohit A, Reig I, Seneviratne SL, Sinaniotis A, Takei M, Versteeg SA, Vassilopoulou AE, Vieths S, Welsing PMJ, Zwinderman AH, Le TM, Van Ree R
誌 名 等：Allergy . 2023 Sep;78(9):2497-2509. Epub 2023 Jun 19.

タイトル：Hospital oral food challenge tests in the coronavirus disease 2019 pandemic: A nationwide survey
筆　　者：Yanagida N, Sugizaki C, Sato S, Ebisawa M
誌 名 等：Clinical and Translational Allergy . 2023 Jul;13(7):e12273.

タイトル：Effect of Maternal Egg Intake During the Early Neonatal Period and Risk of Infant Egg Allergy at 12 Months Among Breastfeeding Mothers: A Randomized Clinical Trial
筆　　者：Nagakura KI, Sato S, Shinahara W, Kido H, Fujita H, Yanai T, Akiyama N, Futamura M, Koga H, Fujiwara M, Kaneko H, Taniguchi H, Makita E, Takahashi K, Yanagida N, Ebisawa M, Urashima M
誌 名 等：JAMA Network Open . 2023 Jul 3;6(7):e2322318.

タイトル：Update on oral and epicutaneous immunotherapy for children with food allergy
筆　　者：Miura Y, Sato S, Yanagida N, Ebisawa M
誌 名 等：Allergo Journal International.2023 Jul 11

タイトル：Facial redness in Japanese adolescents with atopic dermatitis treated with dupilumab: A case series
筆　　者：Hara S, Itonaga T, Nishino M, Yanagida N, Sato S, Ebisawa M
誌 名 等：Journal of Allergy and Clinical Immunology: Global. 2023 Mar 21;2(2):100096.

タイトル：Rapid increases in epinephrine concentration following presumed intra-blood vessel administration via epinephrine autoinjector
筆　　者：Ebisawa M, Kaliner MA, Lowenthal R, Tanimoto S.
誌 名 等：Journal of Allergy and Clinical Immunology: Global . 2023 May 23;2(3):100118

タイトル：Pediatric Allergy and Immunology (PAI) is for polishing with artificial intelligence, but careful use.
筆　　者：Eigenmann P, Akenroye A, Atanaskovic Markovic M, Candotti F, Ebisawa M, Genuneit J, Kalayci Ö, Kollmann D, Leung ASY, Peters RL, Riggioni C.
誌 名 等：Pediatric Allergy and Immunology. 2023 Sep;34(9):e14023.

タイトル：Analysis of the Factors That Affect the Detection Duration of SARS-CoV-2 in Loop Mediated Isothermal Amplification among COVID-19 Inpatients
筆　　者：Maruyama K，Sekiya K，Yanagida N，Nakayama K，Kushida Y，Yasuda S，Fukumoto D，Hosoya S，Moriya H， Katsumi M
誌 名 等：Japanese Journal of Infectious Diseases. 2023 Sep 22;76(5):282-288. Epub 2023 May 31.

タイトル：Long-term prognosis after low-dose peanut challenge for patients with a history of anaphylaxis
筆　　者：Akamatsu N, Nagakura KI, Sato S, Yanagida N, Ebisawa M
誌 名 等：Pediatric Allergy and Immunology. 2023 Oct;34(10):e14031.

タイトル：EAACI guidelines on the diagnosis of IgE-mediated food allergy
筆　　者：Santos AF, Riggioni C, Agache I, Akdis CA, Akdis M, Alvarez-Perea A, Alvaro-Lozano M, Ballmer-Weber B, Barni S, Beyer K, Bindslev-Jensen C, Brough HA, Buyuktiryaki B, Chu D, Del Giacco S, Dunn-Galvin A, Eberlein B, Ebisawa M, Eigenmann P, Eiwegger T, Feeney M, Fernandez-Rivas M, Fisher HR, Fleischer DM, Giovannini M, Gray C, Hoffmann-Sommergruber K, Halken S, Hourihane JO, Jones CJ, Jutel M, Knol E, Konstantinou GN, Lack G, Lau S, Marques Mejias A, Marchisotto MJ, Meyer R, Mortz CG, Moya B, Muraro A, Nilsson C, Lopes de Oliveira LC, O'Mahony L, Papadopoulos NG, Perrett K, Peters RL, et al.
誌 名 等：Allergy . 2023 Dec;78(12):3057-3076. Epub 2023 Oct 10.

タイトル：Global disparities in availability of epinephrine auto-injectors
筆　　者：Tanno LK, Worm M, Ebisawa M, Ansotegui IJ, Senna G, Fineman S, Geller M, Gonzalez-Estrada A, Campbell DE, Leung A, Muraro A, Levin M, Ortega Martell JA, Caminati M, Kolkhir P, Le Pham D, Darlenski R, Esteban-Gorgojo I, Rial M, Filipovic I, Chiarella SE, Cuervo-Pardo L, Kwong C, Pozo-Beltran CF, Trinh TH, Greenberger PA, Turner PJ, Thong BY, Martin B, Cardona V; WAO Anaphylaxis Committee and the WAO Junior Members Steering Group.
誌 名 等：World Allergy Organization Journal. 2023 Oct 20;16(10):100821

タイトル：Safe consumption of processed foods after negative medium-dose cow's milk oral food challenge
筆　　者：Koosakulchai V, Park S, Ban M, Fusayasu N, Yanagida N, Sato S, Ebisawa M
誌 名 等：Allergology International. 2023 Oct 30:S1323-8930(23)00108-9.

タイトル：Real-world compliance and determinants for sublingual allergen immunotherapy in children and parents
筆　　者：Okubo Y, Kuwabara Y, Sato S, Sakashita M, Yuka H, Morita H
誌 名 等：Allergy. 2023 Nov 2.

タイトル：World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update - X - Breastfeeding a baby with cow's milk allergy
筆　　者：McWilliam V, Netting MJ, Volders E, Palmer DJ; WAO DRACMA Guideline Group (Ebisawa18 et al.)
誌 名 等：World Allergy Organization Journal. 2023 Nov 3;16(11):100830.

タイトル：Impact of COVID-19 on care-seeking patterns for hay fever in Japan: A retrospective claims database cohort study
筆　　者：Akasaki Y, Iwagami M, Sung J, Nagino K, Adachi T, Morita H, Tamari M, Kainuma K, Kan-o K, Ogata H, Sakashita M, Futamura M, Kurashima Y, Nakajima S, Masaki K, Ogawa Y, Sato S, Miyagawa A, Midorikawa-Inomata A, Fujimoto K, Okumura Y, Fujio K, Huang T, Hirosawa K, Morooka Y, Nakao S, Murakami A, Kobayashi H, Inomata T
誌 名 等：Allergy. 2023 Nov 15.

タイトル：The utility of macadamia nut legumin Mac i 2 and its conformational epitopes in the diagnosis of macadamia nut allergy
筆　　者：Yamamoto R, Ando T, Kitaura J, Narita M, Miura K, Takasato Y, Nagao M, Okumura K, Ogawa H, Ohnishi H, Watanabe T, Ito K, Fujisawa T, Ebisawa M, Ohya Y, Kabasser S, Bublin M, Yasudo H
誌 名 等：The Journal of Allergy and Clinical Immunology: In Practice. 2023 Nov 19:S2213-2198(23)01261-8.

タイトル：Natural history of cow's milk allergy in children aged 6-12 years
筆　　者：Kubota K, Nagakura KI, Ejiri Y, Sato S, Ebisawa M, Yanagida N
誌 名 等：Pediatric Allergy and Immunology. 2023 Dec;34(12):e14064.

タイトル：Adrenaline auto injectors pharmacokinetic/pharmacodynamic studies and potential consequences for clinical practice
筆　　者：Worm M, Fox AT, Wickman M, Ring J, Ebisawa M, Pouessel G, Smith P
誌 名 等：Clinical and Translational Allergy. 2023 Dec;13(12):e12323.

タイトル：Reaching Communities Through Food Allergy Advocacy, Research, and Education: A Comprehensive Analysis.
筆　　者：Sansweet S, Rolling C Jr, Ebisawa M, Wang J, Gupta R, Davis CM
誌 名 等：Journal of Allergy and Clinical Immunology: In Practice. 2023 Dec 25:S2213-2198(23)01389-2.

タイトル：Editorial comment on "Oral immunotherapy as a curative treatment for food-allergic preschool children: Current evidence and potential underlying mechanisms"
筆　　者：Arasi S, Ebisawa M, Eigenmann P, Dinardo G
誌 名 等：Pediatric Allergy and Immunology. 2024 Jan;35(1):e14071.

タイトル：Three-year prognosis after low-dose oral food challenge for children with wheat allergy
筆　　者：Itonaga T, Yanagida N, Nagakura KI, Asaumi T, Tokunaga M, Nishino M, Takahashi K, Ogura K, Sato S, Ebisawa M
誌 名 等：Allergology International. 2024 Jan 31:S1323-8930(24)00005-4.

タイトル：Editorial comment on "Frequency of fatal and recurrent anaphylaxis due to cow's milk: A systematic review and meta-analysis of observational studies"
筆　　者：Sousa-Pinto B, Alvarez-Perea A, Ebisawa M, Eigenmann P
誌 名 等：Pediatric Allergy and Immunology. 2024 Feb;35(2):e14088.

タイトル：Updated grading system for systemic allergic reactions: Joint Statement of the World Allergy Organization Anaphylaxis Committee and Allergen Immunotherapy Committee
筆　　者：Turner PJ, Ansotegui IJ, Campbell DE, Cardona V, Carr S, Custovic A, Durham S, Ebisawa M, Geller M, Gonzalez-Estrada A, Greenberger PA, Hossny E, Irani C, Leung ASY, Levin ME, Muraro A, Oppenheimer JJ, Ortega Martell JA, Pouessel G, Rial MJ, Senna G, Tanno LK, Wallace DV, Worm M, Morais-Almeida M; WAO Anaphylaxis Committee and WAO Allergen Immunotherapy Committee.
誌 名 等：World Allergy Organization Journal. 2024 Feb 10;17(3):100876.

タイトル：Timing of initial symptom onset during milk and wheat challenges: A retrospective study
筆　　者：Yanagida N, Minoura T, Sato S, Takahashi K, Nagakura KI, Ogura K, Itonaga T, Miura Y, Fusayasu N, Ebisawa M.
誌 名 等：Immunity, Inflammation and Disease. 2024 Feb;12(2):e1174.

タイトル：Authors' response
筆　　者：Tanimoto S, Kaliner M, Lockey R, Ebisawa M
誌 名 等：Annals of Allergy, Asthma & Immunology.2024 Mar.;132(3):402

タイトル：Disparities in pediatric anaphylaxis triggers and management across Asia
筆　　者：Leung ASY, Tham EH, Pacharn P, Xing Y, Trinh HKT, Lee S, Ahn K, Chatchatee P, Sato S, Ebisawa M, Lee BW, Wong GWK; Asia-Pacific Research Network for Anaphylaxis (APRA)
誌 名 等：Allergy. 2024 Mar 10.

タイトル：Precision allergy molecular diagnosis applications in food allergy
筆　　者：Sato S, Ebisawa M
誌 名 等：Current Opinion in Allergy and Clinical Immunology. 2024 Mar 27.

タイトル：Management of food allergy based on oral food challenge
筆　　者：Ishibashi S, Yanagida N, Sato S, Ebisawa M
誌 名 等：Current Opinion in Allergy and Clinical Immunology. 2024 Mar 28.

タイトル：Preparing Patients for Oral Immunotherapy (PPOINT): International Delphi consensus for procedural preparation and consent.
筆　　者：Mack DP, Dribin TE, Turner PJ, Wasserman RL, Hanna MA, Shaker M, Tang MLK, Rodríguez Del Río P, Sobolewski B, Abrams EM, Anagnostou A, Arasi S, Bajowala S, Bégin P, Cameron SB, Chan ES, Chinthrajah S, Clark AT, Detjen P, du Toit G, Ebisawa M, Elizur A, Factor JM, Greiwe J, O'B Hourihane J, Hughes SW, Jones DH, Muraro A, Nowak-Wegrzyn A, Patel NB, Scurlock AM, Shah AN, Sindher SB, Tilles S, Vickery BP, Wang J, Windom HH, Greenhawt M.
誌 名 等：Journal of Allergy and Clinical Immunology. 2024 Mar 28:S0091-6749(24)00238-0.

【和文原著】

タイトル：消費者庁「食物アレルギーに関連する食品表示に関する調査研究事業」令和 2（2020）年即時型食物アレルギー全国モニタリング調査結果報告
筆　　者：杉崎 千鶴子, 髙橋 亨平, 佐藤 さくら, 柳田 紀之, 海老澤 元宏
誌 名 等：アレルギー 2023．9；72（8）：1032-1037

タイトル：アトピー性皮膚炎の長期コントロール指標Recap of atopic eczema（RECAP）の日本語版の作成と言語検証
筆　　者：糸永 宇慧, 柳田 紀之, 西野 誠, 佐藤 さくら, 大松 華子, 大竹 直人, 牧田 英士, 福家 辰樹, 三浦 太郎, 千代反田 雅子, 鈴木 誠, 真部 哲治, 小池 由美, 二村 昌樹, 長尾 みづほ, 緒方 美佳, 高山 良子, 杉山 晃子, 片岡 葉子, 石氏 陽三, 益田 浩司, 田中 暁生, 中原 剛士, 室田 浩之, 佐伯 秀久, 加藤 則人, 海老澤 元宏
誌 名 等：アレルギー 2023．12；72（10）：1240-1247

タイトル：食物アレルギー児の養育者自身のQuality of Life質問票開発と検証
筆　　者：川野 聖明, 高瀬 章弘, 安成 大輔, 本村 知華子, 池田 政憲, 松井 照明, 緒方 美佳, 鈴木 修一, 手塚 純一郎, 長尾 みづほ, 増本 夏子, 柳田 紀之, 大矢 幸弘
誌 名 等：アレルギー 2024．3；73（2）：180-188

2022年度

【欧文原著・総説・著書】

タイトル：Recent advances in diagnosing and managing nut allergies with focus on hazelnuts, walnuts, and cashew nuts
筆　　者：Borres MP, Sato S, Ebisawa M
誌 名 等：World Allergy Organization Journal.2022 Apr.;15(4): 100641

タイトル：World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guideline update - XIV - Recommendations on CMA immunotherapy.
筆　　者：Brozek JL, Ebisawa M, et al
誌 名 等：World Allergy Organization Journal.2022 Apr.;15(4): 100646

タイトル：Long-term follow-up of fixed low-dose oral immunotherapy for children with wheat-induced anaphylaxis
筆　　者：Nagakura KI, Yanagida N, Miura Y, Itonaga T, Nishino M, Takahashi K, Ogura K, Sato S, Ebisawa M
誌 名 等：J Allergy Clin Immunol Pract. 2022 Apr; 10(4):1117-1119.e2. Epub 2021 Dec 23.

タイトル：Is oral food challenge test useful for avoiding complete elimination of cow's milk in Japanese patients with or suspected of having IgE-dependent cow's milk allergy?
筆　　者：Maeda M, Kuwabara Y, Tanaka Y, Nishikido T, Hiraguchi Y, Yamamoto-Hanada K, Okafuji I, Yamada Y, Futamura M, Ebisawa M.
誌 名 等：Allergology International. 2022 Apr; 71(2):214-220. Epub 2021 Sep 27.

タイトル：Is oral food challenge useful to avoid complete elimination in Japanese patients diagnosed with or suspected of having IgE-dependent hen's egg allergy? A systematic review
筆　　者：Murai H, Irahara M, Sugimoto M, Takaoka Y, Takahashi K, Wada T, Yamamoto-Hanada K, Okafuji I, Yamada Y, Futamura M, Ebisawa M.
誌 名 等：Allergology International. 2022 Apr; 71(2):221-229. Epub 2021 Oct 16.

タイトル：History of immediate reactions changes the predictive accuracy for pediatric peanut allergy
筆　　者：Fusayasu N, Asaumi T, Takahashi K, Nagakura KI, Nishino M, Sato S, Yanagida N, Ebisawa M.
誌 名 等：Allergology International. 2022 Apr; 71(2):248-250. Epub 2021 Oct 18.

タイトル：Capsicum Allergy: Involvement of Cap a 7, a New Clinically Relevant Gibberellin-Regulated Protein Cross-Reactive With Cry j 7, the Gibberellin-Regulated Protein From Japanese Cedar Pollen
筆　　者：Takei M, Nin C, Iizuka T, Pawlikowski M, Selva MA, Chantran Y, Nakajima Y, Zheng J, Aizawa T, Ebisawa M, Sénéchal H, Poncet P.
誌 名 等：Allergy Asthma Immunology Research.2022 May.; 14(3):328-338

タイトル：Editorial comments on: "Food allergy in early childhood increases the risk of pollen food allergy syndrome".
筆　　者：Eigenmann P, Ebisawa M.
誌 名 等：Pediatr Allergy Immunol.2022 May.; 33(5): e13788

タイトル：WAO-ARIA consensus on chronic cough - Part III: Management strategies in primary and cough-specialty care. Updates in COVID-19.
筆　　者：Rouadi PW, Ebisawa M, et al
誌 名 等：World Allergy Organization Journal.2022 May.; 15(5): 100649

タイトル：Standards for practical intravenous rapid drug desensitization & delabeling: A WAO committee statement.
筆　　者：Alvarez-Cuesta E, et al, Collaborators:Ebisawa M, et al
誌 名 等：World Allergy Organization Journal.2022 May.; 15(6): 100640

タイトル：Research impact analysis of international funding agencies in the realm of allergy and immunology
筆　　者：Adachi T,Sato S, et al
誌 名 等：Allergy. 2022 May.;77(5):1602-1606. Epub 2022 Feb 16.

タイトル：Predictive value of 7S globulin-specific IgE in Japanese macadamia nut allergy patients
筆　　者：Yasudo H,Ebisawa M, et al
誌 名 等：J Allergy Clin Immunol Pract. 2022 May.;10(5):1389-1391.e1. Epub 2022 Jan 21.

タイトル：Personalized management for unmet needs with food allergy.
筆　　者：Miura Y, Yanagida N, Sato S, Ebisawa M.
誌 名 等：Curr Opin Allergy Clin Immunol. 2022 Jun.; 22(3): 160-166

タイトル：One-year safety and tolerability of tezepelumab in Japanese patients with severe uncontrolled asthma: results of the NOZOMI study.
筆　　者：Shinkai M, Ebisawa M, Fukushima Y, Takeuchi S, Okada H, Tokiyo T, Hayashi N, Takikawa M, Colice G, Almqvist G.
誌 名 等：J Asthma. 2023 Mar.;60(3):616-624.Epub 2022 Jun 16.

タイトル：Presentation of airway and general symptoms in Covid-19 caused by dominant SARS-CoV-2 variants: a follow-up on ARIA consensus
筆　　者：Hagemann J,et al. , ARIA group: Ebisawa M, et al.
誌 名 等：Allergy. 2022 Jun.; 10.1111/all.15416

タイトル：Proposal of 0.5mg of protein /100g of processed food as threshold for voluntary declaration of food allergen traces in processed food - a first step in an initiative to better inform patients and avoid fatal allergic reactions - A GA²LEN position paper
筆　　者：Zuberbier T, Ebisawa M et al
誌 名 等：Allergy. 2022 Jun.; 77(6):1736-1750. Epub 2021 Nov 24.

タイトル：Cashew allergy diagnosis: a two-step algorithm leads to fewer oral food challenges
筆　　者：Brettig T, Koplin JJ, Dang T, Lange L, McWilliam V, Sato S, Savvatianos S, Perrett KP
誌 名 等：J Allergy Clin Immunol Pract. 2022 Jun;10(6):1652-1654.e2. Epub 2022 Jan 21.

タイトル：Cross-reactivity of each fraction among cereals in children with wheat allergy.
筆　　者：Takei M, Saito A, Yanagida N, Sato S, Ebisawa M.
誌 名 等：Pediatr Allergy Immunol. 2022 Jul.; 33(7): e13831

タイトル：Diversities of allergic pathologies and their modifiers: Report from the second DGAKI-JSA meeting.
筆　　者：Asano K, Tamari M, Zuberbier T, Yasudo H, Morita H, Fujieda S, Nakamura Y, Traidl S, Hamelmann E, Raap U, Babina M, Nagase H, Okano M, Katoh N, Ebisawa M, Renz H, Izuhara K, Worm M.
誌 名 等：Allergol Int. 2022 Jul.; 71(3): 310-317

タイトル：Threshold and safe ingestion dose among infants sensitized to hen's egg.
筆　　者：Mitomori M, Yanagida N, Nishino M, Takahashi K, Nagakura KI, Ogura K, Takei M, Sato S, Ebisawa M.
誌 名 等：Pediatr Allergy Immunol. 2022 Jul.; 33(7): e13830

タイトル：Evaluation of adrenaline auto-injector prescription profiles: Apopulation-based, retrospective cohort study within the NationalInsurance Claims Database of Japan
筆　　者：Sato S, et al
誌 名 等：Allergology International. 2022 Jul.; 71(3):354-361. Epub 2022 Mar 21.

タイトル：Ana o 3 sIgE and diagnostic algorithms reduce cost of cashew allergy diagnosis in children compared with skin prick test: A cost comparison analysis
筆　　者：Brettig T, Dalziel K, Koplin JJ, Dang T, Lange L, McWilliam V, Sato S, Savvatianos S, Perrett KP.
誌 名 等：Pediatric Allergy and Immunology.2022 Aug.; 33(8):

タイトル：Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study.
筆　　者：Ishizuka T, Menzies-Gow A, Okada H, Fukushima Y, Hayashi N, Colice G, Ponnarambil S, Hunter G, Odajima H, Ebisawa M.
誌 名 等：Allergol Int. 2022 Aug.; S1323-8930(22): 00082-X

タイトル：COVID-19 vaccination in patients receiving allergen immunotherapy (AIT) or biologicals-EAACI recommendations
筆　　者：Jutel M, Ebisawa M, et al
誌 名 等：Allergy. 2022 Aug.; 77(8):2313-2336. Epub 2022 Mar 18.

タイトル：Macadamia nut-specific IgE levels for predicting anaphylaxis.
筆　　者：Kubota K, Nagakura KI, Itonaga T, Sato S, Ebisawa M, Yanagida N.
誌 名 等：Pediatr Allergy Immunol. 2022 Sep.; 33(9): e13852

タイトル：Efficacy of dupilumab in patients with uncontrolled, moderate-to-severe asthma recruited from Japanese centers in the phase 3 LIBERTY ASTHMA TRAVERSE study.
筆　　者：Tohda Y, Nakamura Y, Fujisawa T, Ebisawa M, Msihid J, Djandji M, Ortiz B, Jacob-Nara JA, Deniz Y, Rowe PJ, Ishida M, Arima K.
誌 名 等：PAllergol Int. 2022 Sep.; 13:S1323-8930(22): 00087-9

タイトル：Managing food allergy: GA2LEN guideline 2022.
筆　　者：Muraro A, Ebisawa M et al.
誌 名 等：World Allergy Organization Journal. 2022 Sep.; 15(9): 100687

タイトル：World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guideline update - XIII - Oral immunotherapy for CMA - Systematic review.
筆　　者：Bognanni A, et al.,WAO DRACMA Guideline Group:Ebisawa M, et al
誌 名 等：World Allergy Organization Journal. 2022 Sep.; 15(9): 100682

タイトル：Systematic review of monotherapy with biologicals for children and adults with IgE-mediated food allergy.
筆　　者：de Silva D, Singh C, Arasi S, Muraro A, Zuberbier T, Ebisawa M, Alvaro Lozano M, Roberts G.
誌 名 等：Clin Transl Allergy. 2022 Sep.; 12(9): e12123

タイトル：Updated threshold dose-distribution data for sesame.
筆　　者：Turner PJ, Gretzinger M, Patel N, Brough H, Chinthrajah RS, Ebisawa M, Elizur A, Koplin JJ, Peters RL, Purington N, Nowak-Wegrzyn A, Saf S, Sampson HA, Westerhout J, Blom WM, Baumert JL, Houben GF, Remington BC.
誌 名 等：Allergy. 2022 Oct.; 77(10): 3124-3162

タイトル：Updated full range of Eliciting Dose values for Cow's milk for use in food allergen risk assessment.
筆　　者：Blom WM, Westerhout J, Baumert JL, Meima MY, Turner PJ, Ebisawa M, Yanagida N, Remington BC, Houben GF.
誌 名 等：Food Chem Toxicol. 2022 Oct.; 168: 113381

タイトル：Editorial Comment on: The role of short-term grass pollen exposure in food skin-prick test reactivity, food allergy, and eczema flares in children.
筆　　者：Ebisawa M, Eigenmann P.
誌 名 等：Pediatr Allergy Immunol. 2022 Oct.; 33(10): e13866

タイトル：Risk Factors for Lung Function Decline in Pediatric Asthma under Treatment: A Retrospective, Multicenter, Observational Study.
筆　　者：Yamada S, Fujisawa T, Nagao M, Matsuzaki H, Motomura C, Odajima H, Nakamura T, Imai T, Nagakura KI, Yanagida N, Mitomori M, Ebisawa M, Kabashima S, Ohya Y, Habukawa C, Tomiita M, Hirayama M.
誌 名 等：Children (Basel). 2022 Oct.; 9(10): 1516

タイトル：Phenotyping of immediate-type food allergies based on 10 years of research: A latent class analysis
筆　　者：Takahashi K, Yanagida N, Itonaga T, Nishino M, Nagakura KI, Ogura K, Sato S, Ebisawa M
誌 名 等：Pediatric Allergy and Immunology.2022 Nov.; 33(11): 13873

タイトル：Clinical cross-reactivity of wheat and barley in children with wheat allergy
筆　　者：Yanagida N, Takei M, Saito A, Sato S, Ebisawa M.
誌 名 等：Pediatric Allergy and Immunology.2022 Nov.; 33(11): 13878

タイトル：Real-world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities
筆　　者：Sousa-Pinto B, Ebisawa M, et al
誌 名 等：Clinical and Translational Allergy.2022 Nov.; 12(11): e12208

タイトル：Pharmacokinetic and Pharmacodynamic Comparison of Epinephrine administered intranasally and intramuscularly: an integrated analysis.
筆　　者：Tanimoto S, Kaliner M, Lockey RF, Ebisawa M, Koplowitz LP, Koplowitz B, Lowenthal R.
誌 名 等：Ann Allergy Asthma Immunol. 2022 Nov.; S1081-1206(22): 01904-4

タイトル：Pharmacokinetic and pharmacodynamic comparison of epinephrine, administered intranasally and intramuscularly: An integrated analysis
筆　　者：Tanimoto S, Kaliner M, Lockey RF, Ebisawa M, Koplowitz LP, Koplowitz B, Lowenthal R
誌 名 等：Annals of Allergy, Asthma & Immunology.2022 Nov.; S1081-1206(22): 01904-4

タイトル：Risk factors for failing a repeat oral food challenge in preschool children with hen's egg allergy.
筆　　者：Nishino M, Yanagida N, Sato S, Nagakura KI, Takahashi K, Ogura K, Ebisawa M
誌 名 等：Pediatric Allergy and Immunology.2022 Dec.; 33(12): e13895

タイトル：Sensitization to macadamia 7S globulin amino-terminus with clinical relevance in Japanese children with macadamia nut allergy
筆　　者：Ando T, Kitaura J, Maruyama N, Narita M, Miura K, Takasato Y, Nogami K, Nagao M, Okumura K, Ogawa H, Onishi H, Watanabe T, Ito K, Fujisawa T, Ebisawa M, Kawakami T, Matsumoto K, Hasegawa S, Ohya Y, Yasudo H
誌 名 等：Allergology International.2022 Dec.; S1323-8930(22): 00130-7

タイトル：Current situation of anaphylaxis in Japan: Data from the anaphylaxis registry of training and teaching facilities certified by the Japanese Society of Allergy - secondary publication.
筆　　者：Sato S, Yanagida N, Ito K, Okamoto Y, Saito H, Taniguchi M, Nagata M, Hirata H, Yamaguchi M, Pawankar R, Ebisawa M
誌 名 等：Allergology International.2022 Dec.; S1323-8930(22): 00140-X

タイトル：Varying Approaches to Management of IgE-Mediated Food Allergy in Children Around the World.
筆　　者：Lloyd M, Loke P, Mack DP, Sicherer SH, Perkin MR, Boyle R, Yin Leung AS, Lee BW, Levin M, Blumchen K, Fiocchi A, Ebisawa M, Oliveira LCL, Tang MLK.
誌 名 等：Journal of Allergy and Clinical Immunology.2023 Feb.; S2213-2198(23): 00175-7

タイトル：EAACI Molecular Allergology User's Guide 2.0
筆　　者：Dramburg S, Hilger C, Santos AF, de Las Vecillas L, Aalberse RC, Acevedo N, Aglas L, Altmann F, Arruda KL, Asero R, Ballmer-Weber B, Barber D, Beyer K, Biedermann T, Bilo MB, Blank S, Bosshard PP, Breiteneder H, Brough HA, Bublin M, Campbell D, Caraballo L, Caubet JC, Celi G, Chapman MD, Chruszcz M, Custovic A, Czolk R, Davies J, Douladiris N, Eberlein B, Ebisawa M, Ehlers A, Eigenmann P, Gadermaier G, Giovannini M, Gomez F, Grohman R, Guillet C, Hafner C, Hamilton RG, Hauser M, Hawranek T, Hoffmann HJ, Holzhauser T, Iizuka T, Jacquet A, Jakob T, Janssen-Weets B, Jappe U, Jutel M, Kalic T, Kam
誌 名 等：Pediatric Allergy and Immunology. 2023 Mar;34 Suppl 28:e13854.

タイトル：WAO consensus on DEfinition of Food Allergy SEverity (DEFASE).
筆　　者：Arasi S, Ebisawa M et al.
誌 名 等：World Allergy Organization Journal.2023 Mar.; 16(3): 100753

タイトル：Enhanced early skin treatment for atopic dermatitis in infants reduces food allergy
筆　　者：Yamamoto-Hanada K, Kobayashi T, Mikami M, Williams HC, Saito H, Saito-Abe M, Sato M, Irahara M, Miyaji Y, Ishikawa F, Tsuchiya K, Tamagawa-Mineoka R, Takaoka Y, Takemura Y, Sato S, Wakiguchi H, Hoshi M, Natsume O, Yamaide F, Seike M, Ohya Y; PACI Study investigators.
誌 名 等：Journal of Allergy and Clinical Immunology. 2023 Jul;152(1):126-135. . Epub 2023 Mar 22.

タイトル：Prognosis of infantile food protein-induced enterocolitis syndrome to wheat: A case series
筆　　者：Nishino M, Yanagida N, Sato S, Nagakura KI, Takahashi K, Ogura K, Ebisawa M.
誌 名 等：Pediatric Allergy and Immunology. 2023 Mar;34(3):e13940.

タイトル：Barrier Factors of Adherence to Dupilumab Self-Injection for Severe Allergic Disease: A Non-Interventional Open-Label Study
筆　　者：Hosoya K, Komachi T, Masaki K, Suzaki I, Saeki H, Kanda N, Nozaki M, Kamide Y, Matsuwaki Y, Kobayashi Y, Ogino E, Osada SI, Usukura N, Kurumagawa T, Ninomia J, Asako M, Nakamoto K, Yokoi H, Ohyama M, Tanese K, Kanzaki S, Fukunaga K, Ebisawa M, Okubo K.
誌 名 等：Patient Preference and Adherence. 2023 Mar 27;17:861-872.

タイトル：Oral Immunotherapy in Food Allergy: Where Are We Now?
筆　　者：Özdemir PG, Sato S, Yanagida N, Ebisawa M.
誌 名 等：Allergy, Asthma and Immunology Research. 2023 Mar;15(2):125-144.

タイトル：Relationship between serum allergen-specific immunoglobulin E and threshold dose in an oral food challenge
筆　　者：Yanagida N, Sato S, Nagakura KI, Takahashi K, Fusayasu N, Miura Y, Itonaga T, Ogura K, Ebisawa M.
誌 名 等：Pediatric Allergy and Immunology . 2023 Mar;34(3):e13926.

【和文原著】

タイトル：医薬品　副作用データベース(Japanese Adverse Drug Event Report database　JADER)を利用した医薬品によるアナフィラキシー症例の解析
筆　　者：杉崎 千鶴子,佐藤 さくら,柳田 紀之,海老澤 元宏
誌 名 等：アレルギー　2022. 5；71(3)：231-241

2021年度

【欧文原著・総説・著書】

タイトル：Food protein-induced enterocolitis syndrome triggered by egg yolk and egg white
筆　　者：Nishino M, Sato S, Nagakura KI, Takahashi K, Asaumi T, Ogura K, Ebisawa M, Yanagida N.
誌 名 等：Pediatric Allergy and Immunology. 2021 Apr;32(3):618-621. Epub 2020 Nov 29.

タイトル：Timing of onset of allergic symptoms following low-dose milk and egg challenges
筆　　者：Yanagida N, Sato S, Takahashi K, Ohtani K, Emura S, Shibukawa Y, Murano A, Komata T, Ishida W, Fujita H, Asaumi T, Nagakura KI, Ogura K, Ebisawa M.
誌 名 等：Pediatric Allergy and Immunology. 2021 Apr,;32(3):612-615. Epub 2021 Jan 13.

タイトル：Management of anaphylaxis due to COVID-19 vaccines in the elderly
筆　　者：Bousquet J, Ebisawa M, et al
誌 名 等：Pediatr Allergy. 2021 Oct.;76(10):2952-2964

タイトル：Addressing risk management difficulties in children with food allergies
筆　　者：Eigenmann PA, Ebisawa M, Greenhawt M, Hourihane JO, Perry TT, Remington BC, Wood RA.
誌 名 等：Pediatr Allergy Immunol.2021 May.;32(4):658-666

タイトル：Prevention and management of allergic reactions to food in child care centers and schools: Practice guidelines
筆　　者：Waserman S, Cruickshank H, Hildebrand KJ, Mack D, Bantock L, Bingemann T, Chu DK, Cuello-Garcia C, Ebisawa M, Fahmy D, Fleischer DM, Galloway L, Gartrell G, Greenhawt M, Hamilton N, Hourihane J, Langlois M, Loh R, Muraro A, Rosenfield L, Schoessler S, Tang MLK, Weitzner B, Wang J, Brozek JL.
誌 名 等：Journal of Allergy and Clinical Immunology.2021 May.;147(5):1561-1578.

タイトル：Precision medicine reaching out to the patients in allergology - a German-Japanese workshop report
筆　　者：Pfaar O, Blumchen K, Boateng E, Hamelmann E, Iinuma T, Jakob T, Krauss-Etschmann S, Nagase H, Nakajima S, Nakano T, Renz H, Sato S, Taube C, Wagenmann M, Werfel T, Worm M, Izuhara K.
誌 名 等：Japanese Journal of Infectious Diseases. 2021 May.;5: 162-179.

タイトル：Long-term follow-up of fixed low-dose oral immunotherapy for children with severe cow's milk allergy
筆　　者：Miura Y, Nagakura KI, Nishino M, Takei M, Takahashi K, Asaumi T, Ogura K, Sato S, Ebisawa M, Yanagida N.
誌 名 等：Pediatr Allergy Immunol. 2021 May.;32(4):734-741. Epub 2021 Jan 24.

タイトル：Loop-Mediated Isothermal Amplification for Diagnosing SARS-CoV-2 Infection in Two School Children and a Neonate
筆　　者：Kubota K, Nagakura KI, Ebisawa M, Kaneda G, Yanagida N.
誌 名 等：Japanese Journal of Infectious Diseases. 2022 Jan.;75(1):86-88. Epub 2021 May 31.

タイトル：The challenges of chronic urticaria part 1: Epidemiology, immunopathogenesis, comorbidities, quality of life, and management
筆　　者：Sánchez-Borges M, Ansotegui IJ, Baiardini I, Bernstein J, Canonica GW, Ebisawa M, Gomez RM, González-Diaz S, Martin B, Morais de Almeida M, Ortega Martell JA.
誌 名 等：World Allergy Organization Journal.2021 Jun.;14(6):100533

タイトル：The challenges of chronic urticaria part 2: Pharmacological treatment, chronic inducible urticaria, urticaria in special situations
筆　　者：Sánchez-Borges M, Ansotegui IJ, Baiardini I, Bernstein J, Canonica GW, Ebisawa M, Gomez RM, González-Diaz S, Martin B, Morais de Almeida M, Ortega Martell JA.
誌 名 等：World Allergy Organization Journal.2021 Jun.;14(6):100546

タイトル：Editorial: Food allergy: from defense to attack
筆　　者：Fiocchi A, Ebisawa M.
誌 名 等：Current Opinion in Allergy and Clinical Immunology.2021 Jun.;21(3):261-262

タイトル：ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy
筆　　者：Bousquet J,Ebisawa M, et al
誌 名 等：Clinical and Translational Allergy.2021 Jun.;11(4):e12014

タイトル：Food-induced anaphylaxis morbidity: emergency department and hospitalizations data support preventive strategies
筆　　者：Tanno LK, Clark E, Mamodaly M, Cardona V, Ebisawa M, Asontegui I, Sanchez-Borges M, Santos AF, Fiocchi A, Worm M, Caimmi D, Latour Staffeld P, Muraro A, Pawankar R, Greenberger PA, Thong BY, Martin B, Demoly P.
誌 名 等：Padiatric Allergy and Immunology 2021 Nov.;32(8):1730-1742. Epub 2021 Jul 21.

タイトル：Erratum to "IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper" [World Allergy Organ J 13/2 (2020) 100080]
筆　　者：Ansotegui IJ, Ebisawa M et al
誌 名 等：World Allergy Organization Journal.2021 Jun.;14(7):100557

タイトル：Low-dose oral immunotherapy for walnut allergy with anaphylaxis: Three case reports
筆　　者：Sasamoto K, Nagakura KI, Sato S, Yanagida N, Ebisawa M
誌 名 等：Allergol Int.2021 Jul.;70(3):392-394.

タイトル：EAACI guideline: preventing the development of food allergy in infants and young children (2020 update)
筆　　者：Halken S, Muraro A, de Silva D, Khaleva E, Angier E, Arasi S, Arshad H, Bahnson HT, Beyer K, Boyle R, du Toit G, Ebisawa M, Eigenmann P, Grimshaw K, Hoest A, Jones C, Lack G, Nadeau K, O'Mahony L, Szajewska H, Venter C, Verhasselt V, Wong GW, Roberts G; European Academy of Allergy and Clinical Immunology Food Allergy and Anaphylaxis Guidelines Group.
誌 名 等：Pediatr Allergy Immunol.2021 Jul.;32(5):843-858.

タイトル：Gibberellin-regulated protein sensitization in Japanese cedar (Cryptomeria japonica) pollen allergic Japanese cohorts
筆　　者：Iizuka T, Takei M, Saito Y, Rumi F, Zheng J, Lu X, Chafey P, Broussard C, Guilloux L, Charpin D, Ebisawa M, Sénéchal H, Aizawa T, Poncet P
誌 名 等：Allergy. 2021 Jul.;76(7):2297-2302. Epub 2021 Mar 28.

タイトル：Differentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold- An ARIA-EAACI-GA2 LENconsensus
筆　　者：Hagemann J, Ebisawa M, et al
誌 名 等：Allergy. 2021 Aug.; 76(8):2354-2366. Epub 2021 May 14.

タイトル：Precision medicine for cow's milk immunotherapy in clinical practice
筆　　者：Miura Y, Nagakura KI, Sato S, Yanagida N, Ebisawa M.
誌 名 等：Current Opinion in Allergy and Clinical Immunology.2021 Aug.;21(4):378-385

タイトル：Peanut Can Be Used as a Reference Allergen for Hazard Characterization in Food Allergen Risk Management: A Rapid Evidence Assessment and Meta-Analysis
筆　　者：Turner PJ, Ebisawa M et al
誌 名 等：J Allergy Clin Immunol Pract. 2022 Jan.; 10(1):59-70. Epub 2021 Aug 23.

タイトル：Low-dose oral immunotherapy for walnut allergy with anaphylaxis: Three case reports
筆　　者：Sasamoto K, Nagakura KI, Sato S, Yanagida N, Ebisawa M
誌 名 等：Allergology International.2021 Jul.;70(3):392-394

タイトル：Treatment-requiring accidental ingestion and risk factors among nursery children with food allergy
筆　　者：Yanagida N, Ebisawa M, Katsunuma T, Yoshizawa J
誌 名 等：Pediatric Allergy and Immunology.2021 Aug.;32(6):1377-1380. Epub 2021 Apr 18.

タイトル：Differentiation of COVID-19 signs and symptoms from allergic rhinitis and common cold: An ARIA-EAACI-GA 2 LEN consensus
筆　　者：Hagemann J, Ebisawa M, et al
誌 名 等：Allergy.2021 Aug.;76(8):2354-2366

タイトル：Natural History of Allergy to Hen's Egg: A Prospective Study in Children Aged 6 to 12 Years
筆　　者：Taniguchi H, Ogura K, Sato S, Ebisawa M, Yanagida N.
誌 名 等：International Archives of Allergy and Immunology. 2022 Jan.; 183(1):14-24. Epub 2021 Sep 1.

タイトル：Oral Wheat Immunotherapy: Long-Term Follow-Up in Children with Wheat Anaphylaxis
筆　　者：Babaie D, Ebisawa M, Soheili H, Ghasemi R, Zandieh F, Sahragard M, Seifi H, Fallahi M, Khoshmirsafa M, Darougar S, Mesdaghi M.
誌 名 等：International Archives of Allergy and Immunology 2022 Feb.; 183:306–314.Epub 2021 Nov 16.

タイトル：WAO-ARIA consensus on chronic cough - Part II: Phenotypes and mechanisms of abnormal cough presentation - Updates in COVID-19
筆　　者：Rouadi PW, Ebisawa M, de al
誌 名 等：World Allergy Organization Journal.2021 Nov.;14(12):100618

タイトル：WAO-ARIA consensus on chronic cough - Part 1: Role of TRP channels in neurogenic inflammation of cough neuronal pathways
筆　　者：Rouadi PW, Ebisawa M, et al
誌 名 等：World Allergy Organization Journal.2021 Dec.;14(12):100617

タイトル：Food allergen ladders: A need for standardization
筆　　者：Venter C, Meyer R, Ebisawa M, Athanasopoulou P, Mack DP
誌 名 等：Pediatr Allergy Immunol.2022 Jan.;33(1):e13714

タイトル：World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - I - Plan and definitions
筆　　者：Fiocchi A, Bognanni A, Brożek J, Ebisawa M, Schünemann H; WAO DRACMA guideline group.
誌 名 等：World Allergy Organ J.2022 Feb.;15(1):100609

タイトル：Clinical cross-reactivity to quail's egg in patients with hen's egg allergy
筆　　者：Mitomori M, Yanagida N, Takei M, Tada K, Nishino M, Sato S, Ebisawa M
誌 名 等：Pediatr Allergy Immunol.2022 Mar.;33(3):e13754

タイトル：Anaphylaxis to winter melon due to cross-reactivity of sensitization to ragweed pollen
筆　　者：Nagakura KI, Takei M, Sato S, Yanagida N, Ebisawa M.
誌 名 等：Pediatr Allergy Immunol.2022 Mar.;33(3):e13764

【和文原著】

タイトル：食物アレルギー児の保育所受け入れ状況等に関する実態調査
筆　　者：林 典子, 柳田 紀之, 小倉 聖剛, 髙橋 亨平, 朴 善美, 渡邉 八寿子, 佐々木 渓円, 佐藤 さくら, 海老澤 元宏
誌 名 等：アレルギー　2021. 6；70(4)：293-301

タイトル：日本のアナフィラキシーの実態：日本アレルギー学会認定教育研修施設におけるアナフィラキシー症例の集積調査
筆　　者：佐藤 さくら, 柳田 紀之, 伊藤 浩明, 岡本 美孝, 斎藤 博久, 谷口 正実, 永田 真, 平田 博国, 山口 正雄, ルビー・パワンカール, 海老澤 元宏
誌 名 等：アレルギー　2022. 3；71(2)：120-129

内科系リウマチ

2023年度

【欧文原著・総説・著書】

タイトル：Accumulation of polyunsaturated fatty acid-derived metabolites in the sarcopenic muscle of aging mice
筆　　者：Kadoguchi T, Shimada K, Fukui N, Tanaka N, Tsuno H, Shiozawa T, Fukao K, Nishitani-Yokoyama M, Isoda K, Matsushita S, Yokoyama N, Daida H
誌 名 等：Geriatrics and Gerontology International . 2023 Apr;23(4):297-303. Epub 2023 Feb 22.

タイトル：Associations of HLA Polymorphisms with Chronic Kidney Disease in Japanese Rheumatoid Arthritis Patients
筆　　者：Higuchi T, Oka S, Furukawa H, Shimada K, Hashimoto A, Komiya A, Matsui T, Fukui N, Tohma S
誌 名 等：Genes (Basel). 2023 Jul 19;14(7):1470.

タイトル：Challenges faced by nurses engaged in rheumatology care in Japan
筆　　者：Fusama M, Nakahara H, Gregg M, Kuroe Y, Urata Y, Kawahata K, Kawahito Y, Kojima M, Sugihara T, Hashimoto M, Miyamae T, Murashima A, Mori M, Yajima N, Matsui T
誌 名 等：Modern Rheumatology. 2023 Aug 4:road079.

タイトル：Analysis of proteins released from osteoarthritic cartilage by compressive loading
筆　　者：Tsuno H, Tanaka N, Naito M, Ohashi S, Iwasawa M, Kadoguchi T, Mitomi H, Matsui T, Furukawa H, Fukui N
誌 名 等：Scientific Reports. 2023 Oct 25;13(1):18292.

タイトル：Association of a Single Nucleotide Variant in TERT with Airway Disease in Japanese Rheumatoid Arthritis Patients
筆　　者：Higuchi T, Oka S, Furukawa H, Shimada K, Tsunoda S, Ito S, Okamoto A, Fujimori M, Nakamura T, Katayama M, Saisho K, Shinohara S, Matsui T, Migita K, Nagaoka S, Tohma S
誌 名 等：Genes (Basel). 2023 Nov 16;14(11):2084.

タイトル：Comparison between rheumatoid arthritis with malignant lymphoma and other malignancies: Analysis of a National Database of Rheumatic Disease in Japan
筆　　者：Mizushima M, Sugihara T, Matsui T, Urata Y, Tohma S, Kawahata K
誌 名 等：Seminars in Arthritis and Rheumatism. 2023 Dec:63:152301. Epub 2023 Nov 3.

タイトル：Factors associated with impaired physical function in elderly rheumatoid arthritis patients who had achieved low disease activity
筆　　者：Komiya Y, Sugihara T, Hirano F, Matsumoto T, Kamiya M, Sasaki H, Hosoya T, Kimura N, Ishizaki T, Mori M, Tohma S, Yasuda S, Matsui T.
誌 名 等：Modern rheumatology. 2023 Dec 22;34(1):60-67

タイトル：New Aspects of Clinical and Immunological Characteristics in Patients with Anti-asparaginyl tRNA synthetase (anti-KS) Autoantibody
筆　　者：Hosono Y, Ishi A, Izumi Y, Sasaki N, Nogi S, Yamada C, Sato S.
誌 名 等：Modern Rheumatology. 2023 Dec 22;34(1):122-128

タイトル：Human leucocyte antigens and Japanese patients with polymyalgia rheumatica: the protective effect of DRB1*09:01
筆　　者：Nogi S, Oka S, Higuchi T, Furukawa H, Shimada K, Azuma T, Sugiyama T, Hirano F, Okamoto A, Fujimori M, Horai Y, Ihata A, Hashimoto A, Komiya A, Matsui T, Fukui N, Katayama M, Migita K, Tohma S
誌 名 等：RMD Open. 2024 Jan 22;10(1):e003897.

タイトル：Trends in Treatment for Patients with Late-onset Rheumatoid Arthritis in Japan: Data from the NinJa Study
筆　　者：Matsui T, Yoshida T, Nishino T, Yoshizawa S, Sawada T, Tohma S
誌 名 等：Mod Rheumatol. 2024 Jan 22:roae006. Online ahead of print.

2022年度

【欧文原著・総説・著書】

タイトル：Lack of association of rs12702634 in RPA3-UMAD1 with interstitial lung diseases in Japanese rheumatoid arthritis patients.
筆　　者：Higuchi T, Oka S, Furukawa H, Shimada K, Tohma S.
誌 名 等：Biomarker Insights. 2022 Apr 15;17:11772719221091758.

タイトル：Detection of SARS-CoV-2 Nucleocapsid, Spike, and Neutralizing Antibodies in Vaccinated Japanese.
筆　　者：Midorikawa R, Nakama M, Furukawa H, Oka S, Higuchi T, Nagai H, Nagai N, Tohma S.
誌 名 等：Viruses. 2022 May 5;14(5):965.

タイトル：Predisposition of HLA-DRB1*04:01/*15 heterozygous genotypes to Japanese mixed connective tissue disease.
筆　　者：Oka S, Higuchi T, Furukawa H, Shimada K, Hashimoto A, Komiya A, Matsui T, Fukui N, Suematsu E, Ohno S, Kono H, Katayama M, Nagaoka S, Migita K, Tohma S
誌 名 等：Scientific Reports.2022 Jun.;12(1):9916

タイトル：Clinical variables, including novel joint index, associated with future patient-physician discordance in global assessment of rheumatoid arthritis (RA) disease activity based on a large RA database in Japan.
筆　　者：Yamamoto Y, Sawada T, Nishiyama S, Tahara K, Hayashi H, Mori H, Kato E, Tago M, Matsui T, Tohma S
誌 名 等：International Journal of Rheumatic Diseases.2022 Sep.;25(9):1020-1028

タイトル：Reversible improvement of arterial stenosis and wall thickness in Takayasu Arteritis through treatment with tocilizumab
筆　　者：Nogi S, Yano Y, Kodama K, Tsuno H, Ogihara H, Kawakami M, Ohmori T, Sato S, Matsui T.
誌 名 等：Annals of Internal Medicine: Clinical Cases.2022 Nov.;

タイトル：Branched chain amino acids in the treatment of polymyositis and dermatomyositis: a phase II/III, multi-center, randomized controlled trial.
筆　　者：Kimura N, Kawahara T, Uemura Y, Atsumi T, Sumida T, Mimura T, Kawaguchi Y, Amano H, Iwasaki Y, Kaneko Y, Matsui T, Muro Y, Imura Y, Kanda T, Tanaka Y, Kawakami A, Jinnin M, Ishii T, Hiromura K, Miwa Y, Nakajima H, Kuwana M, Nishioka Y, Morinobu A, Kameda H, Kohsaka H.
誌 名 等：Rheumatology (Oxford). 2022 Nov.;61(11):4445-4454

タイトル：Social independence evaluation index for Japanese patients with childhood-onset chronic diseases
筆　　者：Inoue Y, Umebayashi H, Matsui T, Nishiyama S, Sakurai I, Maru M, Takeda T, Tanigawa K, Miyamae T.
誌 名 等：Frontiers in Pediatrics.2022 Dec.; 10: 923497. eCollection 2022.

タイトル：Late-onset rheumatoid arthritis registry study, LORIS study: study protocol and design
筆　　者：Kojima M, Kawahito Y, Sugihara T, Kojima T, Harada R, Hirata S, Hashimoto M, Hidaka T, Ishikawa H, Ito H, Kishimoto M, Kaneko Y, Matsui K, Matsui T, Matsushita I, Morinobu A, Nishida K, Tanaka E, Abe A, Ishitoku M, Asai S, Kida T, Onishi A, Takanashi S, Harigai M.
誌 名 等：BMC Rheumatology.2022 Dec.; 6(1): 90

タイトル：Association of a FAM13A variant with interstitial lung disease in Japanese rheumatoid arthritis.
筆　　者：Higuchi T, Oka S, Furukawa H, Shimada K, Tsunoda S, Ito S, Okamoto A, Katayama M, Saisho K, Shinohara S, Matsui T, Migita K, Nagaoka S, Tohma S
誌 名 等：RMD Open. 2023 Jan;9(1):e002828.

タイトル：Antibodies against serum anti-melanoma differentia-tion-associated gene 5 in rheumatoid arthritis patients with chronic lung diseases.
筆　　者：Oka S, Higuchi T, Furukawa H, Shimada K, Okamoto A, Hashimoto A, Komiya A, Saisho K, Yoshikawa N, Katayama M, Matsui T, Fukui N, Migita K, Tohma S
誌 名 等：Medicina (Kaunas, Lithuania). 2023 Feb 14;59(2):363

タイトル：Comprehensive evaluation of the influence of sex differences on composite disease activity indices for rheumatoid arthritis: results from a nationwide observational cohort study.
筆　　者：Nishino T, Hashimoto A, Tohma S, Matsui T.
誌 名 等：BMC Rheumatology. 2023 Mar 21;7(1):4

2021年度

【欧文原著・総説・著書】

タイトル：Marked Effectiveness of Intravenous Immunoglobulin Therapy Against Intractable Lower Leg Ulcers in Two Patients With Rheumatoid Vasculitis.
筆　　者：Nogi S, Hashimoto A, Matsui T.
誌 名 等：JCR: Journal of Clinical Rheumatology.2021 Aug.;27(5):e188-e189

タイトル：Anti-Tumor Necrosis Factor α Therapy Induced Severe Lupus Nephritis in a Patient With Rheumatoid Arthritis.
筆　　者：Kakutani T, Nunokawa T, Hashimoto A, Matsui T.
誌 名 等：J Clin Rheumatol.2021 Apr.;27(3):e104-e105

タイトル：Cutaneous methotrexate-related T-cell lymphoproliferative disorder with CD4, CD30, CD56, EBV-positive tumor cell infiltration: a case illustration and a brief review
筆　　者：Omori I, Kawanabe R, Hashimoto Y, Mitsui A, Kodama K, Nogi S, Tsuno H, Horita A, Saito I, Ohmatsu H
誌 名 等：American Journal Blood Research.2021 Apr.;11(2):163-167

タイトル：Risk of serious infection, malignancy, or death in Japanese rheumatoid arthritis patients treated with a combination of abatacept and tacrolimus: a retrospective cohort study.
筆　　者：Tokunaga K, Matsui K, Oshikawa H, Matsui T, Tohma S
誌 名 等：Clin Rheumatol.2021 May.;40(5):1811-1817

タイトル：Biomarkers for interstitial lung disease and acute-onset diffuse interstitial lung disease in rheumatoid arthritis
筆　　者：Furukawa H, Oka S, Higuchi T, Shimada K, Hashimoto A, Matsui T, Tohma S
誌 名 等：Therapeutic Advances in Musculoskeletal Disease.2021 Jun.;13:1759720X211022506

タイトル：Serum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis.
筆　　者：Oka S, Higuchi T, Furukawa H, Shimada K, Okamoto A, Hashimoto A, Komiya A, Saisho K, Yoshikawa N, Katayama M, Matsui T, Fukui N, Migita K, Tohma S.
誌 名 等：BMC Musculoskelet Disord.2022 Jan.;23(1):46

タイトル：False-positive detection of IgM anti-severe acute respiratory syndrome coronavirus 2 antibodies in patients with rheumatoid arthritis: Possible effects of IgM or IgG rheumatoid factors on immunochromatographic assay results.
筆　　者：Oka S, Higuchi T, Furukawa H, Shimada K, Hashimoto A, Matsui T, Tohma S.
誌 名 等：SAGE Open Medicine. 2022 Mar.;10:20503121221088090. eCollection 2022.

タイトル：Transitioning from paediatric to adult rheumatological healthcare: English summary of the Japanese Transition Support Guide.
筆　　者：Mori M, Akioka S, Igarashi T, Inoue Y, Umebayashi H, Ohshima S, Nishiyama S, Hashimoto M, Matsui T, Miyamae T, Yasumi T.
誌 名 等：Mod Rheumatol.2022 Feb.;32(2):248-255

タイトル：Distal Interphalangeal Joint Involvement May Be Associated with Disease Activity and Affected Joint Distribution in Rheumatoid Arthritis.
筆　　者：Mizuuchi T, Sawada T, Nishiyama S, Tahara K, Hayashi H, Mori H, Kato E, Tago M, Matsui T, Tohma S
誌 名 等：Journal of Clinical Medicine.2022 Mar.;11(5):1405

外科系リウマチ

2023年度

【欧文原著・総説・著書】

タイトル：Predictors for hemostatic thrombin-gelatin matrix usage in spine surgery: a multicenter observational study
筆　　者：Kato S, Miyahara J, Matsubayashi Y, Taniguchi Y, Doi T, Kodama H, Higashikawa A, Takeshita Y, Fukushima M, Ono T, Hara N, Azuma S, Iwai H, Oshina M, Sugita S, Hirai S, Masuda K, Tanaka S, Oshima Y; University of Tokyo Spine Group
誌 名 等：BMC Musculoskeletal Disorders . 2023 Apr 13;24(1):289.

タイトル：Impact of body mass index on outcomes after lumbar spine surgery
筆　　者：Nakajima K, Miyahara J, Ohtomo N, Nagata K, Kato S, Doi T, Matsubayashi Y, Taniguchi Y, Kawamura N, Higashikawa A, Takeshita Y, Fukushima M, Ono T, Hara N, Azuma S, Iwai H, Oshina M, Sugita S, Hirai S, Masuda K, Tanaka S, Oshima Y
誌 名 等：Scientific Reports . 2023 May 15;13(1):7862.

タイトル：Frozen shoulder. An overview of pathology and biology with hopes to novel drug therapies
筆　　者：Tamai K, Hamada J, Nagase Y, Morishige M, Naito M, Asai H, Tanaka S
誌 名 等：Modern Rheumatology . 2023 Aug 26;road087

タイトル：Analysis of proteins released from osteoarthritic cartilage by compressive loading
筆　　者：Tsuno H，Tanaka N，Naito M，Ohashi S，Iwasawa M，Kadoguchi T，Mitomi H，Matsui T，Furukawa H，Fukui N
誌 名 等：Scientific Reports. 2023 Oct 25;13(1):18292.

タイトル：Comparative Analysis of Microendoscopic and Open Laminectomy for Single-Level Lumbar Spinal Stenosis at L1-L2 or L2-L3
筆　　者：Yamato Y, Nagata K, Kawamura N, Higashikawa A, Takeshita Y, Tozawa K, Fukushima M, Urayama D, Ono T, Hara N, Okamoto N, Azuma S, Iwai H, Sugita S, Yoshida Y, Hirai S, Masuda K, Jim Y, Ohtomo N, Nakamoto H, Kato S, Taniguchi Y, Tanaka S, Oshima Y
誌 名 等：World Neurosurgery. 2024年3月:183:e408-e414　Epub 2023年 12 月23 日

2022年度

【欧文原著・総説・著書】

タイトル：Effect of TNF inhibitors with bisphosphonates vs bisphosphonates alone on bone mineral density and bone and cartilage biomarkers at 1 year in patients with rheumatoid arthritis: A prospective study
筆　　者：Nagase Y, Nagashima M, Shimane K, Nishikawa T, Naito M, Tanaka S.
誌 名 等：Modern Rheumatology2022 Apr 18;32(3):517-521.

タイトル：The contribution of deleterious rare alleles in ENPP1 and osteomalacia causative genes to atypical femoral fracture.
筆　　者：Furukawa H, Oka S, Kondo N, Nakagawa Y, Shiota N, Kumagai K, Ando K, Takeshita T, Oda T, Takahashi Y, Izawa K, Iwasaki Y, Hasegawa K, Arino H, Minamizaki T, Yoshikawa N, Takata S, Yoshihara Y, Tohma S.
誌 名 等：The Journal of Clinical Endocrinology & Metabolism.2022 Apr 19;107(5):e1890-e1898.

タイトル：Lumbar Fusion including Sacroiliac Joint Fixation Increases the Stress and Angular Motion at the Hip Joint: A Finite Element Study
筆　　者：Kozaki T, Hashizume H, Oka H, Ohashi S, Kumano Y, Yamamoto E, Minamide A, Yukawa Y, Iwasaki H, Tsutsui S, Takami M, Nakata K, Taniguchi T, Fukui D, Nishiyama D, Yamanaka M, Tamai H, Taiji R, Murata S, Murata A, Yamada H.
誌 名 等：Spine Surgery and Related Research.2022 Apr.; 6(6): 681-688

タイトル：Postoperative outcomes after degenerative lumbar spine surgery in rheumatoid arthritis patients -a propensity score-matched analysis
筆　　者：Kato S, Nakamoto H, Matsubayashi Y, Taniguchi Y, Doi T, Yoshida Y, Higashikawa A, Takeshita Y, Fukushima M, Ono T, Hara N, Okazaki R, Iwai H, Oshina M, Sugita S, Hirai S, Masuda K, Tanaka S, Oshima Y; University of Tokyo Spine Group
誌 名 等：BMC Musculoskeletal Disorders 2022 Apr.;23(1):380

タイトル：Characteristics of gene expression in frozen shoulder
筆　　者：Nishimoto H, Fukuta S, Fukui N, Sairyo K, Yamaguchi T
誌 名 等：BMC Musculoskeletal Disorders 2022 Aug.;23(1):811

タイトル：Evaluation of bone strength using finite-element analysis in patients with ossification of the posterior longitudinal ligament
筆　　者：Doi T, Ohashi S, Ohtomo N, Tozawa K, Nakarai H, Yoshida Y, Ito Y, Sakamoto R, Nakajima K, Nagata K, Okamoto N, Nakamoto H, Kato S, Taniguchi Y, Matsubayashi Y, Tanaka S, Oshima Y.
誌 名 等：The Spine Journal.2022 Aug;22(8):1399-1407.Epub 2022 Mar 5.

タイトル：Accumulation of polyunsaturated fatty acid-derived metabolites in the sarcopenic muscle of aging mice
筆　　者：Kadoguchi T, Shimada K, Fukui N, Tanaka N, Tsuno H, Shiozawa T, Fukao K, Nishitani-Yokoyama M, Isoda K, Matsushita S, Yokoyama N, Daida H.
誌 名 等：Geriatrics and Gerontology International.2023 Fev.:

タイトル：Erratum for Lumbar Fusion including Sacroiliac Joint Fixation Increases the Stress and Angular Motion at the Hip Joint: A Finite Element Study
筆　　者：Kozaki T, Hashizume H, Oka H, Ohashi S, Kumano Y, Yamamoto E, Minamide A, Yukawa Y, Iwasaki H, Tsutsui S, Takami M, Nakata K, Taniguchi T, Fukui D, Nishiyama D, Yamanaka M, Tamai H, Taiji R, Murata S, Murata A, Yamada H.
誌 名 等：Spine Surgery and Related Research. 2023 Mar 27;7(2):199.

【和文原著】

タイトル：Terrible Triad Injuryに対し非連結型人工肘関節置換術を行った1例
筆　　者：荒井 翔,岩澤 三康
誌 名 等：日本職業・災害医学会会誌 2022.7;70(4):160-164

2021年度

【欧文原著・総説・著書】

タイトル：Fracture of ossified Achilles tendons: A review of cases
筆　　者：Ishikura H, Fukui N, Iwasawa M, Ohashi S, Tanaka T, Tanaka S.
誌 名 等：World Journal of Orthopedics.2021 Apr.;12(4):207-213

タイトル：Cutaneous methotrexate-related T-cell lymphoproliferative disorder with CD4, CD30, CD56, EBV-positive tumor cell infiltration: a case illustration and a brief review
筆　　者：Omori I, Kawanabe R, Hashimoto Y, Mitsui A, Kodama K, Nogi S, Tsuno H, Horita A, Saito I, Ohmatsu H
誌 名 等：American Journal Blood Research.2021 Apr.;11(2):163-167

タイトル：Systemic inflammatory responses after orthopedic surgery in patients with rheumatoid arthritis treated with tofacitinib
筆　　者：Uchio A, Matsumoto T, Maenohara Y, Omata Y, Takahashi H, Iwasawa M, Juji T, Nakamura I, Tanaka S.
誌 名 等：Clinical Rheumatology.2021 Dec.;40(12):5077-5083

タイトル：Correction to: Systemic inflammatory responses after orthopedic surgery in patients with rheumatoid arthritis treated with tofacitinib
筆　　者：Uchio A, Matsumoto T, Maenohara Y, Omata Y, Takahashi H, Iwasawa M, Juji T, Nakamura I, Tanaka S.
誌 名 等：Clinical Rheumatology.2021 Dec.;40(12):5085

タイトル：Serum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis.
筆　　者：Oka S, Higuchi T, Furukawa H, Shimada K, Okamoto A, Hashimoto A, Komiya A, Saisho K, Yoshikawa N, Katayama M, Matsui T, Fukui N, Migita K, Tohma S.
誌 名 等：BMC Musculoskelet Disord.2022 Jan.;23(1):46

【和文原著】

タイトル：関節リウマチ治療のため、デノスマブ製剤投与間隔短縮後3年で発症した大腿骨転子下非定型骨折の1例
筆　　者：大坪 研介,大橋 暁,鳥山 義郷
誌 名 等：Hip Joint　2020 .8；47(1)：449-452

タイトル：変形性膝関節症において関節滑膜でのマトリックスメタロプロテアーゼの発現に関与する miRNA の探索
筆　　者：田中信帆, 津野宏隆, 加藤智啓, 福井尚志
誌 名 等：聖マリアンナ医科大学雑誌　2021. 12；49(3)

臨床免疫学分野

2023年度

【欧文原著・総説・著書】

タイトル：Idiotope-Driven T-Cell/B-Cell Collaboration-Based T-Cell Epitope Prediction Using B-Cell Receptor Repertoire Sequences in Infectious Diseases
筆　　者：Nakamura Y, Moi ML, Shiina T, Shin-I T, Suzuki R
誌 名 等：iruses . 2023 May 17;15(5):1186.

タイトル：Pre-existing cross-reactive neutralizing activity against SARS-CoV-2 and seasonal coronaviruses prior to the COVID-19 pandemic (2014-2019) with limited immunity against recent emerging SARS-CoV-2 variants, Vietnam
筆　　者：Nguyen TTN, Choo EM, Nakamura Y, Suzuki R, Shiina T, Shin-I T, Fukuta M, Nguyen CT, Nguyen TTT, Nguyen LKH, Hoang VMP, Morita K, Dang DA, Hasebe F, Le TQM, Moi ML
誌 名 等：International Journal of Infectious Diseases. 2024 Feb:139:109-117. Epub 2023 Nov 19.

2022年度

【欧文原著・総説・著書】

タイトル：Characterization of Metal-Specific T-Cells in Inflamed Oral Mucosa in a Novel Murine Model of Chromium-Induced Allergic Contact Dermatitis
筆　　者：Yoshizawa T, Kumagai K, Matsubara R, Nasu K, Kitaura K, Suzuki M, Hamada Y, Suzuki R
誌 名 等：International Journal of Molecular Sciences.2023 Fev.; 24(3): 2807

タイトル：Type IVb Hypersensitivity Reaction in the Novel Murine Model of Palladium-Induced Intraoral Allergic Contact Mucositis
筆　　者：Nasu K, Kumagai K, Yoshizawa T, Kitaura K, Matsubara R, Suzuki M, Suzuki R, Hamada Y
誌 名 等：International Journal of Molecular Sciences.2023 Feb.; 24(4): 3137

タイトル：Cross-Reactivity of Intraoral Allergic Contact Mucositis in the Nickel-Sensitized Ear Model of Metal Allergy
筆　　者：Matsubara R, Kumagai K, Nasu K, Yoshizawa T, Kitaura K, Suzuki M, Hamada Y, Suzuki R
誌 名 等：International Journal of Molecular Sciences.2023 Feb.; 24(4): 3965

2021年度

【欧文原著・総説・著書】

タイトル：Pharmacological MEK inhibition promotes polyclonal T-cell reconstitution and suppresses xenogeneic GVHD
筆　　者：Itamura H, Shindo T, Muranushi H, Kitaura K, Okada S, Shin-I T, Suzuki R, Takaori-Kondo A, Kimura S.
誌 名 等：Cellular Immunology.2021 Sep.;367:104410

神経難病研究分野

2023年度

【欧文原著・総説・著書】

タイトル：Treatment Methods for Dystonia, Myoclonus, and Chorea
筆　　者：Hasegawa K
誌 名 等：Brain and Nerve. 2023 May;75(5):542-548.

タイトル：Genome-wide association study identifies a new susceptibility locus in PLA2G4C for Multiple System Atrophy
筆　　者：Nakahara Y, Hasegawa K
誌 名 等：medRxiv . 2023 May 2

タイトル：Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients
筆　　者：Nakamura R, Tohnai G, Nakatochi M, Atsuta N, Watanabe H, Ito D, Katsuno M, Hirakawa A, Izumi Y, Morita M, Hirayama T, Kano O, Kanai K, Hattori N, Taniguchi A, Suzuki N, Aoki M, Iwata I, Yabe I, Shibuya K, Kuwabara S, Oda M, Hashimoto R, Aiba I, Ishihara T, Onodera O, Yamashita T, Abe K, Mizoguchi K, Shimizu T, Ikeda Y, Yokota T, Hasegawa K, Tanaka F, Nakashima K, Kaji R, Niwa JI, Doyu M, Terao C, Ikegawa S, Fujimori K, Nakamura S, Ozawa F, Morimoto S, Onodera K, Ito T, Okada Y, Okano H, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis research (JaCALS) study group
誌 名 等：Journal of Neurology, Neurosurgery and Psychiatry . 2023　Oct;94(10):816-824. Epub 2023 May 4.

タイトル：Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome
筆　　者：Aiba I, Hayashi Y, Shimohata T, Yoshida M, Saito Y, Wakabayashi K, Komori T, Hasegawa M, Ikeuchi T, Tokumaru AM, Sakurai K, Murayama S, Hasegawa K, Uchihara T, Toyoshima Y, Saito Y, Yabe I, Tanikawa S, Sugaya K, Hayashi K, Sano T, Takao M, Sakai M, Fujimura H, Takigawa H, Adachi T, Hanajima R, Yokota O, Miki T, Iwasaki Y, Kobayashi M, Arai N, Ohkubo T, Yokota T, Mori K, Ito M, Ishida C, Tanaka M, Idezuka J, Kanazawa M, Aoki K, Aoki M, Hasegawa T, Watanabe H, Hashizume A, Niwa H, Yasui K, Ito K, Washimi Y, Mukai E, Kubota A, Toda T, Nakashima K; J-VAC study group.
誌 名 等：Brain Communications. 2023 Nov 3;5(6):fcad296.

タイトル：Randomized controlled trial of KW-6356 monotherapy in patients with early untreated Parkinson's disease
筆　　者：Maeda T, Kimura T, Sugiyama K, Yamada K, Hiraiwa R, Nishi M, Hattori N; 6356-002 study group.
誌 名 等：Parkinsonism and Related Disorders. 2023 Dec:117:105907.

タイトル：An autopsy case of variably protease-sensitive prionopathy with Met/Met homogeneity at codon 129
筆　　者：Uchino A, Saito Y, Oonuma S, Murayama S, Yagishita S, Kitamoto T, Hasegawa K
誌 名 等：Neuropathology . 2023 Dec;43(6):486-495.　 Epub 2023 May 30.

タイトル：An autopsy case of MV 2K + C subtype of Creutzfeldt-Jakob disease
筆　　者：Uchino A, Saito Y, Tokuda S, Saburo Y, Murayama S, Hasegawa K.
誌 名 等：Neuropathology. 2024 Feb 14.

【和文原著】

タイトル：ジストニア・ミオクロ－ヌス・コレア治療薬
筆　　者：長谷川 一子
誌 名 等：BRAIN and NERVE 2023．5；75（5）：542-548

タイトル：リエゾンを活用した退院支援～病棟看護師の役割と課題～
筆　　者：高橋 八重子,川浪 文,長谷川 一子
誌 名 等：難病と在宅ケア 2023．7；29（4）：49-52

タイトル：中枢神経内の鉄ホメオスタシス
筆　　者：長谷川 一子
誌 名 等：脳神経内科　2023．12；99（6）：723-733

タイトル：Levodopa carbidopa intestinal gel（LCIG）投与時に悪性症候群様症状を呈し，drug-induced lymphocyte stimulation test（DLST）陽性からカルビドパアレルギーが疑われた 70 歳男性
筆　　者：川浪 文,宮下 真信,宮城 雄一,長谷川 一子
誌 名 等：臨床神経学 　2024．1；64（1）：17-22

2022年度

【欧文原著・総説・著書】

タイトル：Mutation screening of the DNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis
筆　　者：Tohnai G, Nakamura R, Atsuta N, Nakatochi M, Hayashi N, Ito D, Watanabe H, Watanabe H, Katsuno M, Izumi Y, Taniguchi A, Kanai K, Morita M, Kano O, Kuwabara S, Oda M, Abe K, Aoki M, Aiba I, Okamoto K, Mizoguchi K, Ishihara T, Kawata A, Yokota T, Hasegawa K, Nagano I, Yabe I, Tanaka F, Kuru S, Hattori N, Nakashima K, Kaji R, Sobue G; Japanese Consortium for Amyotrophic Lateral Sclerosis Research (JaCALS).
誌 名 等：Neurobiology of Aging 2022 May.;113:131-136

タイトル：Age-dependent formation of TMEM106B amyloid filaments in human brains
筆　　者：Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW.
誌 名 等：Nature 2022 May.;605(7909):310-314

タイトル：Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43
筆　　者：Tarutani A, Adachi T, Akatsu H, Hashizume Y, Hasegawa K, Saito Y, Robinson AC, Mann DMA, Yoshida M, Murayama S, Hasegawa M.
誌 名 等：Acta Neuropathologica 2022 May.;1438(6):613-640

タイトル：Structures of α-synuclein filaments from human brains with Lewy pathology
筆　　者：Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M.
誌 名 等：Nature.2022 Oct.; 610(7933): 791-795

タイトル：Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy
筆　　者：Yonenobu Y, Beck G, Kido K, Maeda N, Yamashita R, Inoue K, Saito Y, Hasegawa M, Ito H, Hasegawa K, Morii E, Iwaki T, Murayama S, Mochizuki H.
誌 名 等：Neuropathology.2023 Jan.;

【和文原著】

タイトル：パーキンソニズムを有するレビー小体型認知症患者を対象としたゾニサミド25mg/日を長期投与時の有効性と安全性－第三相試験のポストホック解析－
筆　　者：小田原 俊成,田川 正秋,河内 健治,長谷川 一子
誌 名 等：Dementia Japan 2022.9;36(3):1-13

2021年度

【欧文原著・総説・著書】

タイトル：Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy
筆　　者：Lövestam S,Schweighauser M,Matsubara T,Murayama S,Tomita T,Ando T,Hasegawa K,Yoshida M,Tarutani A,Hasegawa M,Goedert M,H W Scheres S
誌 名 等：FEBS Open Bio.2021 Apr.;11(4):999-1013

タイトル：Cognitive and behavioral status in Japanese ALS patients: a multicenter study
筆　　者：Watanabe Y, Raaphorst J, Izumi Y, Yoshino H, Ito S, Adachi T, Takigawa H, Masuda M, Atsuta N, Adachi Y, Isose S, Arai K, Yokota O, Oda M, Ogino M, Ichikawa H, Hasegawa K, Kimura H, Shimizu T, Aiba I, Yabe H, Kanba M, Kusumi K, Aoki T, Hiroe Y, Watanabe H, Nishiyama K, Nomoto M, Sobue G, Beeldman E, Hanajima R, Nakashima K
誌 名 等：Journal of Neurology.2021 May,;267(5):1321-1330

タイトル：Long-Term Efficacy and Safety of Zonisamide for Treatment of Parkinsonism in Patients With Dementia With Lewy Bodies: An Open-Label Extension of a Phase three Randomized Controlled Trial
筆　　者：Odawara T, Hasegawa K, Kajiwara R, Takeuchi H, Tagawa M, Kosaka K, Murata M.
誌 名 等：The American Journal of Geriatric Psychiatry.2021 Jul.;10:S1064-7481(21)00385-7

タイトル：Human tauopathy-derived tau strains determine the substrates recruited for templated amplification
筆　　者：Tarutani A, Miyata H, Nonaka T, Hasegawa K, Yoshida M, Saito Y, Murayama S, Robinson AC, Mann DMA, Tomita T, Hasegawa M.
誌 名 等：Brain.2021 Sep;144(8):2333-2348

タイトル：Efficacy and Safety of Zonisamide in Dementia with Lewy Bodies Patients with Parkinsonism: A Post Hoc Analysis of Two Randomized, Double-Blind, Placebo-Controlled Trials
筆　　者：Hasegawa K, Kochi K, Maruyama H, Konishi O, Toya S, Odawara T
誌 名 等：Journal of Alzheimer's Disease.2021 Dec.;79(2):627-637

タイトル：Mutation screening of the DNAJC7 gene in Japanese patients with sporadic amyotrophic lateral sclerosis
筆　　者：Tohnai G,Hasegawa K, et al
誌 名 等：Neurobiol Aging.2021 Dec.; Online ahead of print.

タイトル：Efficacy of Wearable Device Gait Training on Parkinson's Disease: A Randomized Controlled Open-label Pilot Study
筆　　者：Kawashima N, Hasegawa K, Iijima M, Nagami K, Makimura T, Kumon A, Ohtsuki S.
誌 名 等：Intern Med. 2022 Sep 1;61(17):2573-2580. Epub 2022 Feb 8.

タイトル：Age-dependent formation of TMEM106B amyloid filaments in human brains
筆　　者：Schweighauser M,Hasegawa K, et al
誌 名 等：Nature. 2022 May;605(7909):310-314.Epub 2022 Mar 28.

鼻アレルギー分野

2023年度

【和文原著】

タイトル：片側顔面神経麻痺を姉妹でほぼ同時に発症した２症例
筆　　者：山口 知子,和佐野 浩一郎,萩原 康平,鈴木 立俊,山下 拓
誌 名 等：FACIAL NERVE RESEARCH JAPAN　2023．7；43：152-153

皮膚アレルギー分野

2023年度

【欧文原著・総説・著書】

タイトル：Rapidly Progressive Multiple Skin Plaques and Nodules: A Quiz
筆　　者：Boki H, Miyagaki T, Suga H, Ohmatsu H, Sato S
誌 名 等：Acta Dermato-Venereologica . 2023 Jun 22

【和文原著】

タイトル：皮膚科専門医講座 皮膚科専門医のための模擬テスト15-解答と解説-
筆　　者：大松 華子
誌 名 等：DERMATOLOGY 皮膚科 2023．4；3（4）：505-509

2022年度

【和文原著】

タイトル：味覚異常がみられたが、Laugier-Hunziker-Baran症候群と考えた1例
筆　　者：川邉 瑠璃子,大森 一星,橋本 優希,三井 彩,大松 華子
誌 名 等：皮膚科の臨床 2022.5;64(6):1111-1115

タイトル：四肢体幹に多発する紫斑と高度蛋白尿を呈し、副腎皮質ステロイドによる積極的治療を要したIgA血管炎
筆　　者：川邉 瑠璃子,大森 一星,橋本 優希,三井 彩,津野 宏隆,荻原 秀樹,大松 華子
誌 名 等：皮膚科の臨床 2022.5;64(6):1055-1059

2021年度

【欧文原著・総説・著書】

タイトル：Cutaneous methotrexate-related T-cell lymphoproliferative disorder with CD4, CD30, CD56, EBV-positive tumor cell infiltration: a case illustration and a brief review
筆　　者：Omori I, Kawanabe R, Hashimoto Y, Mitsui A, Kodama K, Nogi S, Tsuno H, Horita A, Saito I, Ohmatsu H
誌 名 等：American Journal of Blood Research. 2021 Apr.;11(2)：163-167

【和文原著】

タイトル：原発性皮膚 CD30 陽性 T細胞リンパ増殖異常症の１例
筆　　者：岡 謙太,橋本 優希,三宅 温, 三井 彩, 堀田 綾子,齋藤 生朗,大松 華子
誌 名 等：皮膚科の臨床　2021. 4；63(4)：541-544

タイトル：HLA-A26 陽性であった不全型Behcet病の１例
筆　　者：岡 謙太,大森 一星,橋本 優希,三宅 温,三井 彩,津野 宏隆, 堀田 綾子, 齋藤 生朗, 大松 華子
誌 名 等：皮膚科の臨床　2021. 6；63(7)：1096-1100

タイトル：右手に生じ緊満性水疱を伴った水疱性丹毒の1例
筆　　者：大森 一星,岡 謙太,川邉 瑠璃子,橋本 優希,三井 彩,大松 華子
誌 名 等：皮膚科の臨床　2021. 12;63(13):2092-2094

タイトル：常色局面を呈しダーモスコピーで血管性病変がみられた無色素性基底細胞癌の1例
筆　　者：大森 一星,岡 謙太,橋本 優希,三井 彩,堀田 綾子,齋藤 生朗,大松 華子
誌 名 等：皮膚科の臨床　2021. 12;63(13):2071-2074

タイトル：顔面に皮疹が多発した皮膚限局性結節性アミロイドーシスの一例
筆　　者：橋本 優希,三井 彩,三宅 温,岡 謙太,齋藤 生朗,大松 華子
誌 名 等：皮膚科の臨床　2021. 12;64(1):91-94

タイトル：【水疱症】口腔内に限局した粘膜類天疱瘡の一例
筆　　者：大森 一星,川邉 瑠璃子,橋本 優希,三井 彩,重松 宏昭,大松 華子
誌 名 等：皮膚科の臨床　2021. 12;64(1):51-54

腫瘍免疫分野

2021年度

【欧文原著・総説・著書】

タイトル：A single-nucleotide-polymorphism in the 5'-flanking region of MSX1 gene as a predictive marker candidate for platinum-based therapy of esophageal carcinoma
筆　　者：Mori T, Ueno K, Tokunaga K, Kawai Y, Matsuda K, Nishida N, Komine K, Saito S, Nagasaki M; BioBank Japan Project.
誌 名 等：Therapeutic Advances in Medical Oncology.2022 Feb.;14:17588359221080580

臨床外科免疫分野

2023年度

【欧文原著・総説・著書】

タイトル：A Japanese Prospective, Multicenter Study of Colonic Stenting for Palliation Using a High Axial Force Self-Expandable Metal Stent for Malignant Large Bowel Obstruction in 200 Patients
筆　　者：Ishibashi R, Sasaki T, Isayama H, Matsuzawa T, Kuwai T, Yamada T, Saito S, Tomita M, Shiratori T, Ikeda S, Kanazawa H, Fujishiro M, Maetani I, Saida Y.
誌 名 等：Journal of Clinical Medicine.2023 Aug 5;12(15):5134.

業績集

業績集は、PDF形式で公開しております。
研究業績集　令和5年度